Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control

Tekijä Singh, Rajeev, Lauth, Matthias
Julkaisussa J Dev Biol (2017)

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

Tekijä Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Julkaisussa Oncotarget (2016)

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

Tekijä Lauth, Matthias, Spreafico, Fabio, Dethleffsen, Kathrin, Meyer, Michael
Julkaistu 2002

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

Tekijä Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Toftgård, Rune
Julkaistu 2007

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1

Tekijä Palaniswamy, Ramesh, Teglund, Stephan, Lauth, Matthias, Zaphiropoulos, Peter G, Shimokawa, Takashi
Julkaistu 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

Tekijä Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Julkaistu 2016

Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

Tekijä Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Julkaistu 2008

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

Tekijä Barski, Jaroslaw J., Denker, Brad M., Guan, Jiazhen, Lauth, Matthias, Spreafico, Fabio, Fertala, Andrzej, Meyer, Michael
Julkaistu 2013

Inhibition of GLI1 gene activation by Patched1

Tekijä Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
Julkaistu 2006

Chronic Pancreatitis and Systemic Inflammatory Response Syndrome Prevent Impact of Chemotherapy with Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer()()

Tekijä Knoop, Richard F., Sparn, Moritz, Waldmann, Jens, Plassmeier, Lars, Bartsch, Detlef K., Lauth, Matthias, Hudemann, Christoph, Fendrich, Volker
Julkaistu 2014

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

Tekijä Fendrich, Volker, Oh, Edwin, Bang, Seungmin, Karikari, Collins, Ottenhof, Niki, Bisht, Savita, Lauth, Matthias, Brossart, Peter, Katsanis, Nicholas, Maitra, Anirban, Feldmann, Georg
Julkaistu 2011

Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

Tekijä Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Julkaisussa Cancers (Basel) (2021)

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Tekijä Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Julkaisussa Nat Commun (2015)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

Tekijä Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Julkaisussa Nat Commun (2015)

The Immune Microenvironment in Pancreatic Cancer

Tekijä Huber, Magdalena, Brehm, Corinna U., Gress, Thomas M., Buchholz, Malte, Alashkar Alhamwe, Bilal, Pogge von Strandmann, Elke, Slater, Emily P., Bartsch, Jörg W., Bauer, Christian, Lauth, Matthias
Julkaisussa Int J Mol Sci (2020)

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

Tekijä Joost, Simon, Almada, Luciana L., Rohnalter, Verena, Holz, Philipp S., Vrabel, Anne M., Fernandez-Barrena, Maite G., McWilliams, Robert R., Krause, Michael, Fernandez-Zapico, Martin E., Lauth, Matthias
Julkaistu 2011

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Tekijä Luu, Maik, Pautz, Sabine, Kohl, Vanessa, Singh, Rajeev, Romero, Rossana, Lucas, Sébastien, Hofmann, Jörg, Raifer, Hartmann, Vachharajani, Niyati, Carrascosa, Lucia Campos, Lamp, Boris, Nist, Andrea, Stiewe, Thorsten, Shaul, Yoav, Adhikary, Till, Zaiss, Mario M., Lauth, Matthias, Steinhoff, Ulrich, Visekruna, Alexander
Julkaisussa Nat Commun (2019)

Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancer

Tekijä Luu, Maik, Riester, Zeno, Baldrich, Adrian, Reichardt, Nicole, Yuille, Samantha, Busetti, Alessandro, Klein, Matthias, Wempe, Anne, Leister, Hanna, Raifer, Hartmann, Picard, Felix, Muhammad, Khalid, Ohl, Kim, Romero, Rossana, Fischer, Florence, Bauer, Christian A., Huber, Magdalena, Gress, Thomas M., Lauth, Matthias, Danhof, Sophia, Bopp, Tobias, Nerreter, Thomas, Mulder, Imke E., Steinhoff, Ulrich, Hudecek, Michael, Visekruna, Alexander
Julkaisussa Nat Commun (2021)