Emerging Roles of DYRK Kinases in Embryogenesis and Hedgehog Pathway Control

by Singh, Rajeev, Lauth, Matthias
Published in J Dev Biol (2017)

DYRK1B blocks canonical and promotes non-canonical Hedgehog signaling through activation of the mTOR/AKT pathway

by Singh, Rajeev, Dhanyamraju, Pavan Kumar, Lauth, Matthias
Published in Oncotarget (2016)

Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases

by Lauth, Matthias, Spreafico, Fabio, Dethleffsen, Kathrin, Meyer, Michael
Published 2002

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

by Lauth, Matthias, Bergström, Åsa, Shimokawa, Takashi, Toftgård, Rune
Published 2007

Genetic variations regulate alternative splicing in the 5' untranslated regions of the mouse glioma-associated oncogene 1, Gli1

by Palaniswamy, Ramesh, Teglund, Stephan, Lauth, Matthias, Zaphiropoulos, Peter G, Shimokawa, Takashi
Published 2010

Back to the drawing board: Re-thinking the role of GLI1 in pancreatic carcinogenesis

by Hogenson, Tara L., Lauth, Matthias, Pasca diMagliano, Marina, Fernandez-Zapico, Martin E.
Published 2016

Novel Human Glioma-associated Oncogene 1 (GLI1) Splice Variants Reveal Distinct Mechanisms in the Terminal Transduction of the Hedgehog Signal

by Shimokawa, Takashi, Tostar, Ulrica, Lauth, Matthias, Palaniswamy, Ramesh, Kasper, Maria, Toftgård, Rune, Zaphiropoulos, Peter G.
Published 2008

Developmental Upregulation of an Alternative Form of pcp2 with Reduced GDI Activity

by Barski, Jaroslaw J., Denker, Brad M., Guan, Jiazhen, Lauth, Matthias, Spreafico, Fabio, Fertala, Andrzej, Meyer, Michael
Published 2013

Inhibition of GLI1 gene activation by Patched1

by Rahnama, Fahimeh, Shimokawa, Takashi, Lauth, Matthias, Finta, Csaba, Kogerman, Priit, Teglund, Stephan, Toftgård, Rune, Zaphiropoulos, Peter G.
Published 2006

Chronic Pancreatitis and Systemic Inflammatory Response Syndrome Prevent Impact of Chemotherapy with Gemcitabine in a Genetically Engineered Mouse Model of Pancreatic Cancer()()

by Knoop, Richard F., Sparn, Moritz, Waldmann, Jens, Plassmeier, Lars, Bartsch, Detlef K., Lauth, Matthias, Hudemann, Christoph, Fendrich, Volker
Published 2014

Ectopic Overexpression of Sonic Hedgehog (Shh) Induces Stromal Expansion and Metaplasia in the Adult Murine Pancreas

by Fendrich, Volker, Oh, Edwin, Bang, Seungmin, Karikari, Collins, Ottenhof, Niki, Bisht, Savita, Lauth, Matthias, Brossart, Peter, Katsanis, Nicholas, Maitra, Anirban, Feldmann, Georg
Published 2011

Activation of Cilia-Independent Hedgehog/GLI1 Signaling as a Novel Concept for Neuroblastoma Therapy

by Koeniger, Anke, Brichkina, Anna, Nee, Iris, Dempwolff, Lukas, Hupfer, Anna, Galperin, Ilya, Finkernagel, Florian, Nist, Andrea, Stiewe, Thorsten, Adhikary, Till, Diederich, Wibke, Lauth, Matthias
Published in Cancers (Basel) (2021)

Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

by Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Published in Nat Commun (2015)

Correction: Corrigendum: Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1

by Schneider, Philipp, Bayo-Fina, Juan Miguel, Singh, Rajeev, Dhanyamraju, Pavan Kumar, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias
Published in Nat Commun (2015)

The Immune Microenvironment in Pancreatic Cancer

by Huber, Magdalena, Brehm, Corinna U., Gress, Thomas M., Buchholz, Malte, Alashkar Alhamwe, Bilal, Pogge von Strandmann, Elke, Slater, Emily P., Bartsch, Jörg W., Bauer, Christian, Lauth, Matthias
Published in Int J Mol Sci (2020)

GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells

by Joost, Simon, Almada, Luciana L., Rohnalter, Verena, Holz, Philipp S., Vrabel, Anne M., Fernandez-Barrena, Maite G., McWilliams, Robert R., Krause, Michael, Fernandez-Zapico, Martin E., Lauth, Matthias
Published 2011

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

by Luu, Maik, Pautz, Sabine, Kohl, Vanessa, Singh, Rajeev, Romero, Rossana, Lucas, Sébastien, Hofmann, Jörg, Raifer, Hartmann, Vachharajani, Niyati, Carrascosa, Lucia Campos, Lamp, Boris, Nist, Andrea, Stiewe, Thorsten, Shaul, Yoav, Adhikary, Till, Zaiss, Mario M., Lauth, Matthias, Steinhoff, Ulrich, Visekruna, Alexander
Published in Nat Commun (2019)

Microbial short-chain fatty acids modulate CD8(+) T cell responses and improve adoptive immunotherapy for cancer

by Luu, Maik, Riester, Zeno, Baldrich, Adrian, Reichardt, Nicole, Yuille, Samantha, Busetti, Alessandro, Klein, Matthias, Wempe, Anne, Leister, Hanna, Raifer, Hartmann, Picard, Felix, Muhammad, Khalid, Ohl, Kim, Romero, Rossana, Fischer, Florence, Bauer, Christian A., Huber, Magdalena, Gress, Thomas M., Lauth, Matthias, Danhof, Sophia, Bopp, Tobias, Nerreter, Thomas, Mulder, Imke E., Steinhoff, Ulrich, Hudecek, Michael, Visekruna, Alexander
Published in Nat Commun (2021)