Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles

Bằng Lansakara-P, Dharmika S. P., Rodriguez, B. Leticia, Cui, Zhengrong
Được phát hành 2012

Lysosomal delivery of a lipophilic gemcitabine prodrug using novel acid-sensitive micelles improved its antitumor activity

Bằng Zhu, Saijie, Lansakara-P, Dharmika S.P., Li, Xinran, Cui, Zhengrong
Được phát hành 2012

A nanoparticle depot formulation of 4-(N)-stearoyl gemcitabine shows a strong anti-tumour activity

Bằng Zhu, Saijie, Li, Xinran, Lansakara-P, Dharmika S P, Kumar, Amit, Cui, Zhengrong
Được phát hành 2012

Kinetics of Two-Electron Oxidations by the Compound I Derivative of Chloroperoxidase, a Model for Cytochrome P450 Oxidants

Bằng Zhang, Rui, Nagraj, Nandini, Lansakara-P, Dharmika S. P., Hager, Lowell P., Newcomb, Martin
Được phát hành 2006

Stearoyl gemcitabine nanoparticles overcome resistance related to the over-expression of ribonucleotide reductase subunit M1

Bằng Chung, Woon-Gye, Sandoval, Michael A., Sloat, Brian R., Lansakara-P., Dharmika S. P., Cui, Zhengrong
Được phát hành 2011

The effect of the acid-sensitivity of 4-(N)-stearoyl gemcitabine-loaded micelles on drug resistance caused by RRM1 overexpression

Bằng Zhu, Saijie, Wonganan, Piyanuch, Lansakara-P, Dharmika S.P., O’Mary, Hannah L., Li, Yue, Cui, Zhengrong
Được phát hành 2012

Just Getting Into Cells is Not Enough: Mechanisms Underlying 4-(N)-Stearoyl Gemcitabine Solid Lipid Nanoparticle's Ability to Overcome Gemcitabine Resistance Caused by RRM1 Overexp...

Bằng Wonganan, Piyanuch, Lansakara-P, Dharmika S. P., Zhu, Saijie, Holzer, Melisande, Sandoval, Michael A., Warthaka, Mangalika, Cui, Zhengrong
Được phát hành 2013

Antitumor activity of tumor-targeted RNA replicase-based plasmid that expresses interleukin-2 in a murine melanoma model

Bằng Rodriguez, B. Leticia, Blando, Jorge M., Lansakara-P, Dharmika S. P., Kiguchi, Yuriko, DiGiovanni, John, Cui, Zhengrong
Được phát hành 2013

A solid lipid nanoparticle formulation of 4-(N)-docosahexaenoyl 2′, 2′-difluorodeoxycytidine with increased solubility, stability, and antitumor activity

Bằng Valdes, Solange A., Alzhrani, Riyad F., Rodriguez, Andres, Lansakara-P, Dharmika S.P., Thakkar, Sachin G., Cui, Zhengrong
Xuất bản năm Int J Pharm (2019)

EGFR-targeted stearoyl gemcitabine nanoparticles show enhanced anti-tumor activity

Bằng Sandoval, Michael A., Sloat, Brian R., Lansakara-P, Dharmika S.P., Kumar, Amit, Rodriguez, B. Leticia, Kiguchi, Kaoru, DiGiovanni, John, Cui, Zhengrong
Được phát hành 2011

In vitro and in vivo anti-tumor activities of a gemcitabine derivative carried by nanoparticles

Bằng Sloat, Brian R., Sandoval, Michael A., Li, Dong, Chung, Woon-Gye, Lansakara-P., Dharmika S. P., Proteau, Philip J., Kiguchi, Kaoru, DiGiovanni, John, Cui, Zhengrong
Được phát hành 2011

Stearoyl gemcitabine nanoparticles overcome obesity-induced cancer cell resistance to gemcitabine in a mouse postmenopausal breast cancer model

Bằng De Angel, Rebecca E., Blando, Jorge M., Hogan, Matthew G., Sandoval, Michael A., Lansakara-P, Dharmika S.P., Dunlap, Sarah M., Hursting, Stephen D., Cui, Zhengrong
Được phát hành 2013

Desaturase Reactions Complicate the Use of Norcarane as a Mechanistic Probe. Unraveling the Mixture of Twenty-Plus Products Formed in Enzyme-Catalyzed Oxidations of Norcarane

Bằng Newcomb, Martin, Esala, R., Chandrasena, P., Lansakara-P., Dharmika S. P., Kim, Hye-Yeong, Lippard, Stephen J., Beauvais, Laurance G., Murray, Leslie J., Izzo, Viviana, Hollenberg, Paul F., Coon, Minor J.
Được phát hành 2007

Products from Enzyme-Catalyzed Oxidations of Norcarenes

Bằng Newcomb, Martin, Lansakara-P., Dharmika S. P., Kim, Hye-Yeong, Chandrasena, R. Esala P., Lippard, Stephen J., Beauvais, Laurance G., Murray, Leslie J., Izzo, Viviana, Hollenberg, Paul F., Coon, Minor J.
Được phát hành 2007