Stearoyl gemcitabine nanoparticles overcome obesity-induced cancer cell resistance to gemcitabine in a mouse postmenopausal breast cancer model

Obesity is associated with increased breast tumor aggressiveness and decreased response to multiple modalities of therapy in postmenopausal women. Delivering cancer chemotherapeutic drugs using nanoparticles has evolved as a promising approach to improve the efficacy of anticancer agents. However, t...

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Autori principali: De Angel, Rebecca E., Blando, Jorge M., Hogan, Matthew G., Sandoval, Michael A., Lansakara-P, Dharmika S.P., Dunlap, Sarah M., Hursting, Stephen D., Cui, Zhengrong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667876/
https://ncbi.nlm.nih.gov/pubmed/23358472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.23623
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