A nanoparticle depot formulation of 4-(N)-stearoyl gemcitabine shows a strong anti-tumour activity

OBJECTIVES: Depot formulation as a carrier for cytotoxic chemotherapeutic drugs is not well studied. The objective of this study is to test the feasibility of using a subcutaneous depot formulation to administer a cytotoxic anti-cancer drug for systemic therapy. METHODS: A fatty-acid amide prodrug o...

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Bibliographic Details
Main Authors: Zhu, Saijie, Li, Xinran, Lansakara-P, Dharmika S P, Kumar, Amit, Cui, Zhengrong
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539214/
https://ncbi.nlm.nih.gov/pubmed/23278691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2042-7158.2012.01599.x
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