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A nanoparticle depot formulation of 4-(N)-stearoyl gemcitabine shows a strong anti-tumour activity
OBJECTIVES: Depot formulation as a carrier for cytotoxic chemotherapeutic drugs is not well studied. The objective of this study is to test the feasibility of using a subcutaneous depot formulation to administer a cytotoxic anti-cancer drug for systemic therapy. METHODS: A fatty-acid amide prodrug o...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539214/ https://ncbi.nlm.nih.gov/pubmed/23278691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2042-7158.2012.01599.x |
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