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Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles

Gemcitabine hydrochloride (HCl) is approved for the treatment of a wide spectrum of solid tumors. However, the rapid development of resistance often makes gemcitabine less efficacious. In the present study, we synthesized several novel lipophilic monophosphorylated gemcitabine derivatives, incorpora...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lansakara-P, Dharmika S. P., Rodriguez, B. Leticia, Cui, Zhengrong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335205/
https://ncbi.nlm.nih.gov/pubmed/22425885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2012.03.014
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