טוען...

Synthesis and in vitro evaluation of novel lipophilic monophosphorylated gemcitabine derivatives and their nanoparticles

Gemcitabine hydrochloride (HCl) is approved for the treatment of a wide spectrum of solid tumors. However, the rapid development of resistance often makes gemcitabine less efficacious. In the present study, we synthesized several novel lipophilic monophosphorylated gemcitabine derivatives, incorpora...

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מידע ביבליוגרפי
Main Authors: Lansakara-P, Dharmika S. P., Rodriguez, B. Leticia, Cui, Zhengrong
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335205/
https://ncbi.nlm.nih.gov/pubmed/22425885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2012.03.014
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