A simple, bead-based approach for multi-SNP molecular haplotyping

Por Hurley, James D., Engle, Linda J., Davis, Jesse T., Welsh, Adam M., Landers, John E.
Publicado em 2004

Mutant PFN1 causes ALS phenotypes and progressive motor neuron degeneration in mice by a gain of toxicity

Por Yang, Chunxing, Danielson, Eric W., Qiao, Tao, Metterville, Jake, Brown, Robert H., Landers, John E., Xu, Zuoshang
Publicado no Proc Natl Acad Sci U S A (2016)

Genome complexity reduction for SNP genotyping analysis

Por Jordan, Barbara, Charest, Alain, Dowd, John F., Blumenstiel, Justin P., Yeh, Ru-fang, Osman, Asiah, Housman, David E., Landers, John E.
Publicado em 2002

Comparative analysis of C9orf72 and sporadic disease in an ALS clinic population

Por Umoh, Mfon E., Fournier, Christina, Li, Yingjie, Polak, Meraida, Shaw, Latoya, Landers, John E., Hu, William, Gearing, Marla, Glass, Jonathan D.
Publicado no Neurology (2016)

The Role of Copy Number Variation in Susceptibility to Amyotrophic Lateral Sclerosis: Genome-Wide Association Study and Comparison with Published Loci

Por Wain, Louise V., Pedroso, Inti, Landers, John E., Breen, Gerome, Shaw, Christopher E., Leigh, P. Nigel, Brown, Robert H., Tobin, Martin D., Al-Chalabi, Ammar
Publicado em 2009

Structural basis for mutation-induced destabilization of profilin 1 in ALS

Por Boopathy, Sivakumar, Silvas, Tania V., Tischbein, Maeve, Jansen, Silvia, Shandilya, Shivender M., Zitzewitz, Jill A., Landers, John E., Goode, Bruce L., Schiffer, Celia A., Bosco, Daryl A.
Publicado no Proc Natl Acad Sci U S A (2015)

Identification of rare protein disulfide isomerase gene variants in amyotrophic lateral sclerosis patients

Por Gonzalez-Perez, Paloma, Woehlbier, Ute, Chian, Ru-Ju, Sapp, Peter, Rouleau, Guy A., Leblond, Claire S., Daoud, Hussein, Dion, Patrick A., Landers, John E., Hetz, Claudio, Brown, Robert H.
Publicado no Gene (2015)

Mutational Analysis of TARDBP in Neurodegenerative Diseases

Por Ticozzi, Nicola, LeClerc, Ashley Lyn, Van-Blitterswijk, Marka, Keagle, Pamela, McKenna-Yasek, Diane M., Sapp, Peter C., Silani, Vincenzo, Wills, Anne-Marie, Brown, Robert H., Landers, John E.
Publicado em 2009

Characterization of FUS Mutations in Amyotrophic Lateral Sclerosis Using RNA-Seq

Por van Blitterswijk, Marka, Wang, Eric T., Friedman, Brad A., Keagle, Pamela J., Lowe, Patrick, Leclerc, Ashley Lyn, van den Berg, Leonard H., Housman, David E., Veldink, Jan H., Landers, John E.
Publicado em 2013

ALS-linked FUS exerts a gain of toxic function involving aberrant p38 MAPK activation

Por Sama, Reddy Ranjith K., Fallini, Claudia, Gatto, Rodolfo, McKeon, Jeanne E., Song, Yuyu, Rotunno, Melissa S., Penaranda, Saul, Abdurakhmanov, Izrail, Landers, John E., Morfini, Gerardo, Brady, Scott T., Bosco, Daryl A.
Publicado no Sci Rep (2017)

Ribonuclease 4 protects neuron degeneration by promoting angiogenesis, neurogenesis, and neuronal survival under stress

Por Li, Shuping, Sheng, Jinghao, Hu, Jamie K., Yu, Wenhao, Kishikawa, Hiroko, Hu, Miaofen G., Shima, Kaori, Wu, David, Xu, Zhengping, Xin, Winnie, Sims, Katherine B., Landers, John E., Brown, Robert H., Hu, Guo-fu
Publicado em 2012

Deleterious Variants of FIG4, a Phosphoinositide Phosphatase, in Patients with ALS

Por Chow, Clement Y., Landers, John E., Bergren, Sarah K., Sapp, Peter C., Grant, Adrienne E., Jones, Julie M., Everett, Lesley, Lenk, Guy M., McKenna-Yasek, Diane M., Weisman, Lois S., Figlewicz, Denise, Brown, Robert H., Meisler, Miriam H.
Publicado em 2009

A common haplotype within the PON1 promoter region is associated with sporadic ALS

Por Landers, John E., Shi, Lijia, Cho, Ting-Jan, Glass, Jonathan D., Shaw, Christopher E., Leigh, P. Nigel, Diekstra, Frank, Polak, Meraida, Rodriguez-Leyva, Ildefonso, Niemann, Stephan, Traynor, Bryan J., Mckenna-Yasek, Diane, Sapp, Peter C., Al-Chalabi, Ammar, Wills, Anne-Marie A., Brown, Robert H.
Publicado em 2008

Novel mutations support a role for Profilin 1 in the pathogenesis of ALS

Por Smith, Bradley N., Vance, Caroline, Scotter, Emma L., Troakes, Claire, Wong, Chun Hao, Topp, Simon, Maekawa, Satomi, King, Andrew, Mitchell, Jacqueline C., Lund, Karan, Al-Chalabi, Ammar, Ticozzi, Nicola, Silani, Vincenzo, Sapp, Peter, Brown, Robert H., Landers, John E., Al-Sarraj, Safa, Shaw, Christopher E.
Publicado no Neurobiol Aging (2015)

Paraoxonase Gene Mutations in Amyotrophic Lateral Sclerosis

Por Ticozzi, Nicola, LeClerc, Ashley Lyn, Keagle, Pamela, Glass, Jonathan D., Wills, Anne-Marie, van Blitterswijk, Marka, Bosco, Daryl A., Rodriguez-Leyva, Ildefonso, Gellera, Cinzia, Ratti, Antonia, Taroni, Franco, McKenna-Yasek, Diane M., Sapp, Peter C., Silani, Vincenzo, Furlong, Clement E., Brown, Robert H., Landers, John E.
Publicado em 2010

Mutations in the N-terminal Actin-Binding Domain of Filamin C Cause a Distal Myopathy

Por Duff, Rachael M., Tay, Valerie, Hackman, Peter, Ravenscroft, Gianina, McLean, Catriona, Kennedy, Paul, Steinbach, Alina, Schöffler, Wiebke, van der Ven, Peter F.M., Fürst, Dieter O., Song, Jaeguen, Djinović-Carugo, Kristina, Penttilä, Sini, Raheem, Olayinka, Reardon, Katrina, Malandrini, Alessandro, Gambelli, Simona, Villanova, Marcello, Nowak, Kristen J., Williams, David R., Landers, John E., Brown, Robert H., Udd, Bjarne, Laing, Nigel G.
Publicado em 2011

Screening of the PFN1 gene in sporadic ALS and in FTD

Por Tiloca, Cinzia, Ticozzi, Nicola, Pensato, Viviana, Corrado, Lucia, Del Bo, Roberto, Bertolin, Cinzia, Fenoglio, Chiara, Gagliardi, Stella, Calini, Daniela, Lauria, Giuseppe, Castellotti, Barbara, Bagarotti, Alessandra, Corti, Stefania, Galimberti, Daniela, Cagnin, Annachiara, Gabelli, Carlo, Ranieri, Michela, Ceroni, Mauro, Siciliano, Gabriele, Mazzini, Letizia, Cereda, Cristina, Scarpini, Elio, Sorarù, Gianni, Comi, Giacomo P., D'Alfonso, Sandra, Gellera, Cinzia, Ratti, Antonia, Landers, John E., Silani, Vincenzo
Publicado em 2012

Polymorphisms in the GluR2 gene are not associated with amyotrophic lateral sclerosis

Por Bogaert, Elke, Goris, An, Van Damme, Philip, Geelen, Veerle, Lemmens, Robin, van Es, Michael A., van den Berg, Leonard H., Sleegers, Kristel, Verpoorten, Nathalie, Timmerman, Vincent, De Jonghe, Peter, Van Broeckhoven, Christine, Traynor, Bryan J., Landers, John E., Brown, Robert H., Glass, Jonathan D., Al-Chalabi, Ammar, Shaw, Christopher E., Birve, Anna, Andersen, Peter M., Slowik, Agnieszka, Tomik, Barbara, Melki, Judith, Robberecht, Wim, Van Den Bosch, Ludo
Publicado em 2010

Mapping of Gene Expression Reveals CYP27A1 as a Susceptibility Gene for Sporadic ALS

Por Diekstra, Frank P., Saris, Christiaan G. J., van Rheenen, Wouter, Franke, Lude, Jansen, Ritsert C., van Es, Michael A., van Vught, Paul W. J., Blauw, Hylke M., Groen, Ewout J. N., Horvath, Steve, Estrada, Karol, Rivadeneira, Fernando, Hofman, Albert, Uitterlinden, Andre G., Robberecht, Wim, Andersen, Peter M., Melki, Judith, Meininger, Vincent, Hardiman, Orla, Landers, John E., Brown, Robert H., Shatunov, Aleksey, Shaw, Christopher E., Leigh, P. Nigel, Al-Chalabi, Ammar, Ophoff, Roel A., van den Berg, Leonard H., Veldink, Jan H.
Publicado em 2012

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis

Por Goris, An, van Setten, Jessica, Diekstra, Frank, Ripke, Stephan, Patsopoulos, Nikolaos A., Sawcer, Stephen J., van Es, Michael, Andersen, Peter M., Melki, Judith, Meininger, Vincent, Hardiman, Orla, Landers, John E., Brown, Robert H., Shatunov, Aleksey, Leigh, Nigel, Al-Chalabi, Ammar, Shaw, Christopher E., Traynor, Bryan J., Chiò, Adriano, Restagno, Gabriella, Mora, Gabriele, Ophoff, Roel A., Oksenberg, Jorge R., Van Damme, Philip, Compston, Alastair, Robberecht, Wim, Dubois, Bénédicte, van den Berg, Leonard H., De Jager, Philip L., Veldink, Jan H., de Bakker, Paul I.W.
Publicado em 2014