The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease

Yazar: Bosmans, Laura A., Bosch, Lena, Kusters, Pascal J.H., Lutgens, Esther, Seijkens, Tom T.P.
Yayımlandı J Cardiovasc Transl Res (2020)

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

Yazar: Poels, Kikkie, van Leent, Mandy M. T., Reiche, Myrthe E., Kusters, Pascal J. H., Huveneers, Stephan, de Winther, Menno P. J., Mulder, Willem J. M., Lutgens, Esther, Seijkens, Tom T. P.
Yayımlandı Cells (2020)

Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis

Yazar: Aarts, Suzanne ABM, Seijkens, Tom TP, Kusters, Pascal JH, van Tiel, Claudia M, Reiche, Myrthe E, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy PAA, de Winther, Menno PJ, Kooij, Gijs, Lutgens, Esther
Yayımlandı J Pathol (2019)

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

Yazar: Aarts, Suzanne A. B. M., Seijkens, Tom T. P., Kusters, Pascal J. H., van der Pol, Susanne M. A., Zarzycka, Barbara, Heijnen, Priscilla D. A. M., Beckers, Linda, den Toom, Myrthe, Gijbels, Marion J. J., Boon, Louis, Weber, Christian, de Vries, Helga E., Nicolaes, Gerry A. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Yayımlandı J Neuroinflammation (2017)

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death

Yazar: Seijkens, Tom T P, Poels, Kikkie, Meiler, Svenja, van Tiel, Claudia M, Kusters, Pascal J H, Reiche, Myrthe, Atzler, Dorothee, Winkels, Holger, Tjwa, Marc, Poelman, Hessel, Slütter, Bram, Kuiper, Johan, Gijbels, Marion, Kuivenhoven, Jan Albert, Matic, Ljubica Perisic, Paulsson-Berne, Gabrielle, Hedin, Ulf, Hansson, Göran K, Nicolaes, Gerry A F, Daemen, Mat J A P, Weber, Christian, Gerdes, Norbert, de Winther, Menno P J, Lutgens, Esther
Yayımlandı Eur Heart J (2019)

Endothelial TGF-β signalling drives vascular inflammation and atherosclerosis

Yazar: Chen, Pei-Yu, Qin, Lingfeng, Li, Guangxin, Wang, Zheng, Dahlman, James E., Malagon-Lopez, Jose, Gujja, Sharvari, Cilfone, Nicholas A., Kauffman, Kevin J., Sun, Lele, Sun, Hongye, Zhang, Xinbo, Aryal, Binod, Canfran-Duque, Alberto, Liu, Rebecca, Kusters, Pascal, Sehgal, Alfica, Jiao, Yang, Anderson, Daniel G., Gulcher, Jeffrey, Fernandez-Hernando, Carlos, Lutgens, Esther, Schwartz, Martin A., Pober, Jordan S., Chittenden, Thomas W., Tellides, George, Simons, Michael
Yayımlandı Nat Metab (2019)

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

Yazar: Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Yayımlandı Nat Commun (2021)

Vascular CXCR4 limits atherosclerosis by maintaining arterial integrity: evidence from mouse and human studies

Yazar: Döring, Yvonne, Noels, Heidi, van der Vorst, Emiel P.C., Neideck, Carlos, Egea, Virginia, Drechsler, Maik, Mandl, Manuela, Pawig, Lukas, Jansen, Yvonne, Schröder, Katrin, Bidzhekov, Kiril, Megens, Remco T.A., Theelen, Wendy, Klinkhammer, Barbara M., Boor, Peter, Schurgers, Leon, van Gorp, Rick, Ries, Christian, Kusters, Pascal J.H., van der Wal, Allard, Hackeng, Tilman M., Gäbel, Gabor, Brandes, Ralf P., Soehnlein, Oliver, Lutgens, Esther, Vestweber, Dietmar, Teupser, Daniel, Holdt, Lesca M., Rader, Daniel J., Saleheen, Danish, Weber, Christian
Yayımlandı Circulation (2017)

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

Yazar: Chatzigeorgiou, Antonios, Seijkens, Tom, Zarzycka, Barbara, Engel, David, Poggi, Marjorie, van den Berg, Susan, van den Berg, Sjoerd, Soehnlein, Oliver, Winkels, Holger, Beckers, Linda, Lievens, Dirk, Driessen, Ann, Kusters, Pascal, Biessen, Erik, Garcia-Martin, Ruben, Klotzsche-von Ameln, Anne, Gijbels, Marion, Noelle, Randolph, Boon, Louis, Hackeng, Tilman, Schulte, Klaus-Martin, Xu, Aimin, Vriend, Gert, Nabuurs, Sander, Chung, Kyoung-Jin, Willems van Dijk, Ko, Rensen, Patrick C. N., Gerdes, Norbert, de Winther, Menno, Block, Norman L., Schally, Andrew V., Weber, Christian, Bornstein, Stefan R., Nicolaes, Gerry, Chavakis, Triantafyllos, Lutgens, Esther
Baskı/Yayın Bilgisi 2014

Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis

Yazar: Seijkens, Tom T.P., van Tiel, Claudia M., Kusters, Pascal J.H., Atzler, Dorothee, Soehnlein, Oliver, Zarzycka, Barbara, Aarts, Suzanne A.B.M., Lameijer, Marnix, Gijbels, Marion J., Beckers, Linda, den Toom, Myrthe, Slütter, Bram, Kuiper, Johan, Duchene, Johan, Aslani, Maria, Megens, Remco T.A., van ‘t Veer, Cornelis, Kooij, Gijs, Schrijver, Roy, Hoeksema, Marten A., Boon, Louis, Fay, Francois, Tang, Jun, Baxter, Samantha, Jongejan, Aldo, Moerland, Perry D., Vriend, Gert, Bleijlevens, Boris, Fisher, Edward A., Duivenvoorden, Raphael, Gerdes, Norbert, de Winther, Menno P.J., Nicolaes, Gerry A., Mulder, Willem J.M., Weber, Christian, Lutgens, Esther
Yayımlandı J Am Coll Cardiol (2018)