Genetic and environmental determinants of human TCR repertoire diversity

Autor Krishna, Chirag, Chowell, Diego, Gönen, Mithat, Elhanati, Yuval, Chan, Timothy A.
Vydáno v Immun Ageing (2020)

Qa-1(b) modulates resistance to anti-PD-1 immune checkpoint blockade in tumors with defects in antigen processing

Autor Zhang, Xiao, Sabio, Erich, Krishna, Chirag, Ma, Xiaoxiao, Wang, Jingming, Jiang, Hui, Havel, Jonathan J., Chan, Timothy A.
Vydáno v Mol Cancer Res (2021)

Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection

Autor Geary, Clair D., Krishna, Chirag, Lau, Colleen M., Adams, Nicholas M., Gearty, Sofia V., Pritykin, Yuri, Thomsen, Allan R., Leslie, Christina S., Sun, Joseph C.
Vydáno v Cell Rep (2018)

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

Autor Chowell, Diego, Krishna, Chirag, Pierini, Federica, Makarov, Vladimir, Rizvi, Naiyer A., Kuo, Fengshen, Morris, Luc G. T., Riaz, Nadeem, Lenz, Tobias L., Chan, Timothy A.
Vydáno v Nat Med (2019)

ILC1 confer early host protection at initial sites of viral infection

Autor Weizman, Orr-El, Adams, Nicholas M., Schuster, Iona, Krishna, Chirag, Pritykin, Yuri, Lau, Colleen, Degli-Esposti, Mariapia A., Leslie, Christina S., Sun, Joseph C., O’Sullivan, Timothy E.
Vydáno v Cell (2017)

Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12

Autor Weizman, Orr-El, Song, Eric, Adams, Nicholas M., Hildreth, Andrew D., Riggan, Luke, Krishna, Chirag, Aguilar, Oscar A., Leslie, Christina S., Carlyle, James R., Sun, Joseph C., O’Sullivan, Timothy E.
Vydáno v Nat Immunol (2019)

In situ vaccination with defined factors overcomes T cell exhaustion in distant tumors

Autor Khalil, Danny N., Suek, Nathan, Campesato, Luis Felipe, Budhu, Sadna, Redmond, David, Samstein, Robert M., Krishna, Chirag, Panageas, Katherine S., Capanu, Marinela, Houghton, Sean, Hirschhorn, Daniel, Zappasodi, Roberta, Giese, Rachel, Gasmi, Billel, Schneider, Michael, Gupta, Aditi, Harding, James J., Moral, John Alec, Balachandran, Vinod P., Wolchok, Jedd D., Merghoub, Taha
Vydáno v J Clin Invest (2019)

Genetic diversity of tumors with mismatch repair deficiency influences anti–PD-1 immunotherapy response

Autor Mandal, Rajarsi, Samstein, Robert M., Lee, Ken-Wing, Havel, Jonathan J., Wang, Hao, Krishna, Chirag, Sabio, Erich Y., Makarov, Vladimir, Kuo, Fengshen, Blecua, Pedro, Ramaswamy, Apoorva T., Durham, Jennifer N., Bartlett, Bjarne, Ma, Xiaoxiao, Srivastava, Raghvendra, Middha, Sumit, Zehir, Ahmet, Hechtman, Jaclyn F., Morris, Luc GT, Weinhold, Nils, Riaz, Nadeem, Le, Dung T., Diaz, Luis A., Chan, Timothy A.
Vydáno v Science (2019)

Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy

Autor Samstein, Robert M., Krishna, Chirag, Ma, Xiaoxiao, Pei, Xin, Lee, Ken-Wing, Makarov, Vladimir, Kuo, Fengshen, Chung, Jonathan, Srivastava, Raghvendra M., Purohit, Tanaya A., Hoen, Douglas R, Mandal, Rajarsi, Setton, Jeremy, Wu, Wei, Shah, Rachna, Qeriqi, Besnik, Chang, Qing, Kendall, Sviatoslav, Braunstein, Lior, Weigelt, Britta, Carrillo Albornoz, Pedro Blecua, Morris, Luc G.T., Mandelker, Diana L, Reis-Filho, Jorge S., de Stanchina, Elisa, Powell, Simon N., Chan, Timothy A., Riaz, Nadeem
Vydáno v Nat Cancer (2020)

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Autor Yang, Wei, Lee, Ken-Wing, Srivastava, Raghvendra M., Kuo, Fengshen, Krishna, Chirag, Chowell, Diego, Makarov, Vladimir, Hoen, Douglas, Dalin, Martin G., Wexler, Leonard, Ghossein, Ronald, Katabi, Nora, Nadeem, Zaineb, Cohen, Marc A., Tian, S. Ken, Robine, Nicolas, Arora, Kanika, Geiger, Heather, Agius, Phaedra, Bouvier, Nancy, Huberman, Kety, Vanness, Katelynd, Havel, Jonathan J., Sims, Jennifer S., Samstein, Robert M., Mandal, Rajarsi, Tepe, Justin, Ganly, Ian, Ho, Alan L., Riaz, Nadeem, Wong, Richard J., Shukla, Neerav, Chan, Timothy A., Morris, Luc G.T.
Vydáno v Nat Med (2019)

Single cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy

Autor Krishna, Chirag, DiNatale, Renzo G., Kuo, Fengshen, Srivastava, Raghvendra M., Vuong, Lynda, Chowell, Diego, Gupta, Sounak, Vanderbilt, Chad, Purohit, Tanaya A., Liu, Ming, Kansler, Emily, Nixon, Briana G., Chen, Ying-Bei, Makarov, Vladimir, Blum, Kyle A., Attalla, Kyrollis, Weng, Stanley, Salmans, Michael L., Golkaram, Mahdi, Liu, Li, Zhang, Shile, Vijayaraghavan, Raakhee, Pawlowski, Traci, Reuter, Victor, Carlo, Maria I., Voss, Martin H., Coleman, Jonathan, Russo, Paul, Motzer, Robert J., Li, Ming O., Leslie, Christina S., Chan, Timothy A., Hakimi, A. Ari
Vydáno v Cancer Cell (2021)