CFTR Modulator Therapies in Pediatric Cystic Fibrosis: Focus on Ivacaftor

由 Kramer, Elizabeth L., Clancy, John P.
發表在 Expert Opin Orphan Drugs (2016)

Subacute TGFβ expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function

由 Kramer, Elizabeth L., Hardie, William D., Madala, Satish K., Davidson, Cynthia, Clancy, John P.
發表在 Am J Physiol Lung Cell Mol Physiol (2018)

2045 The role of TGFβ in driving early cystic fibrosis lung disease

由 Kramer, Elizabeth L., Hardie, William, Hudock, Kristin, Davidson, Cynthia, Ostmann, Alicia, Clancy, John P.
發表在 J Clin Transl Sci (2018)

Subacute TGFβ Exposure Drives Airway Hyperresponsiveness in Cystic Fibrosis Mice through the PI3K Pathway

由 Kramer, Elizabeth L., Madala, Satish K., Hudock, Kristin M., Davidson, Cynthia, Clancy, John P.
發表在 Am J Respir Cell Mol Biol (2020)

Rapamycin Attenuates Airway Hyperreactivity, Goblet Cells, and IgE in Experimental Allergic Asthma

由 Mushaben, Elizabeth M., Kramer, Elizabeth L., Brandt, Eric B., Hershey, Gurjit K. Khurana, Le Cras, Timothy D.
出版 2011

Sensitive Structural and Functional Measurements and 1-Year Pulmonary Outcomes in Pediatric Cystic Fibrosis

由 Willmering, Matthew M., Roach, David J., Kramer, Elizabeth L., Walkup, Laura L., Cleveland, Zackary I., Woods, Jason C.
發表在 J Cyst Fibros (2020)

3123 TGFbeta, Early Cytokine Dysregulation, and Airway Smooth Muscle Dysfunction in Cystic Fibrosis

由 Kramer, Elizabeth L, Szczesniak, Rhonda, Su, Weiji, Madala, Satish, Hudock, Kristin, Davidson, Cynthia, Ostmann, Alicia, Strecker, Lauren, Clancy, John P.
發表在 J Clin Transl Sci (2019)

Chronic β2AR stimulation limits CFTR activation in human airway epithelia

由 Brewington, John J., Backstrom, Jessica, Feldman, Amanda, Kramer, Elizabeth L., Moncivaiz, Jessica D., Ostmann, Alicia J., Zhu, Xiaoting, Lu, L. Jason, Clancy, John P.
發表在 JCI Insight (2018)

FIBROCYTE ACCUMULATION IN THE LUNGS OF CYSTIC FIBROSIS PATIENTS

由 Kasam, Rajesh K., Gajjala, Prathibha R., Jegga, Anil G., Courtney, Jennifer A., Randell, Scott H., Kramer, Elizabeth L., Clancy, John P., Madala, Satish K.
發表在 J Cyst Fibros (2020)

Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease

由 Kramer, Elizabeth L., Hardie, William D., Mushaben, Elizabeth M., Acciani, Thomas H., Pastura, Patricia A., Korfhagen, Thomas R., Hershey, Gurjit Khurana, Whitsett, Jeffrey A., Le Cras, Timothy D.
出版 2011

Early Growth Response-1 Suppresses Epidermal Growth Factor Receptor–Mediated Airway Hyperresponsiveness and Lung Remodeling in Mice

由 Kramer, Elizabeth L., Mushaben, Elizabeth M., Pastura, Patricia A., Acciani, Thomas H., Deutsch, Gail H., Khurana Hershey, Gurjit K., Korfhagen, Thomas R., Hardie, William D., Whitsett, Jeffrey A., Le Cras, Timothy D.
出版 2009

Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma

由 Le Cras, Timothy D., Acciani, Thomas H., Mushaben, Elizabeth M., Kramer, Elizabeth L., Pastura, Patricia A., Hardie, William D., Korfhagen, Thomas R., Sivaprasad, Umasundari, Ericksen, Mark, Gibson, Aaron M., Holtzman, Michael J., Whitsett, Jeffrey A., Khurana Hershey, Gurjit K.
出版 2011

Neutrophil extracellular traps activate IL-8 and IL-1 expression in human bronchial epithelia

由 Hudock, Kristin M., Collins, Margaret S., Imbrogno, Michelle, Snowball, John, Kramer, Elizabeth L., Brewington, John J., Gollomp, Kandace, McCarthy, Cormac, Ostmann, Alicia J., Kopras, Elizabeth J., Davidson, Cynthia R., Srdiharan, Anusha, Arumugam, Paritha, Sengupta, Shaon, Xu, Yan, Worthen, G. Scott, Trapnell, Bruce C., Clancy, John Paul
發表在 Am J Physiol Lung Cell Mol Physiol (2020)

Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis

由 Gardner, Aaron I., Haq, Iram J., Simpson, A. John, Becker, Katrin A., Gallagher, John, Saint-Criq, Vinciane, Verdon, Bernard, Mavin, Emily, Trigg, Alexandra, Gray, Michael A., Koulman, Albert, McDonnell, Melissa J., Fisher, Andrew J., Kramer, Elizabeth L., Clancy, John P., Ward, Christopher, Schuchman, Edward H., Gulbins, Erich, Brodlie, Malcolm
發表在 Am J Respir Crit Care Med (2020)