3123 TGFbeta, Early Cytokine Dysregulation, and Airway Smooth Muscle Dysfunction in Cystic Fibrosis

OBJECTIVES/SPECIFIC AIMS: This study aims to first describe the unique cytokine profile and TGFbeta levels of young children with CF, then understand the pathologic effects of TGFbeta on lung function in a CF animal model. These powerful translational studies linking observations in clinical disease...

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Detalhes bibliográficos
Publicado no:J Clin Transl Sci
Main Authors: Kramer, Elizabeth L, Szczesniak, Rhonda, Su, Weiji, Madala, Satish, Hudock, Kristin, Davidson, Cynthia, Ostmann, Alicia, Strecker, Lauren, Clancy, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cambridge University Press 2019
Assuntos:
Basic/Translational Science/Team Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6799262/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2019.55
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