Small-Molecule Inhibitors of Chikungunya Virus: Mechanisms of Action and Antiviral Drug Resistance

di Kovacikova, Kristina, van Hemert, Martijn J.
Pubblicato in Antimicrob Agents Chemother (2020)

Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses

di Hussain, Saira, Turnbull, Matthew L., Wise, Helen M., Jagger, Brett W., Beard, Philippa M., Kovacikova, Kristina, Taubenberger, Jeffery K., Vervelde, Lonneke, Engelhardt, Othmar G., Digard, Paul
Pubblicato in J Virol (2019)

Suramin Inhibits Chikungunya Virus Replication by Interacting with Virions and Blocking the Early Steps of Infection

di Albulescu, Irina C., White-Scholten, Leonie, Tas, Ali, Hoornweg, Tabitha E., Ferla, Salvatore, Kovacikova, Kristina, Smit, Jolanda M., Brancale, Andrea, Snijder, Eric J., van Hemert, Martijn J.
Pubblicato in Viruses (2020)

Identification of 6′-β-fluoro-homoaristeromycin as a potent inhibitor of chikungunya virus replication

di Shin, Young Sup, Jarhad, Dnyandev B., Jang, Min Hwan, Kovacikova, Kristina, Kim, Gyudong, Yoon, Ji-seong, Kim, Hong-Rae, Hyun, Young Eum, Tipnis, Amol S., Chang, Tong-Shin, van Hemert, Martijn J., Jeong, Lak Shin
Pubblicato in Eur J Med Chem (2020)

6′-β-Fluoro-Homoaristeromycin and 6′-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 1...

di Kovacikova, Kristina, Morren, Bas M., Tas, Ali, Albulescu, Irina C., van Rijswijk, Robin, Jarhad, Dnyandev B., Shin, Young Sup, Jang, Min Hwan, Kim, Gyudong, Lee, Hyuk Woo, Jeong, Lak Shin, Snijder, Eric J., van Hemert, Martijn J.
Pubblicato in Antimicrob Agents Chemother (2020)

Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

di Abdelnabi, Rana, Kovacikova, Kristina, Moesslacher, Julia, Donckers, Kim, Battisti, Verena, Leyssen, Pieter, Langer, Thierry, Puerstinger, Gerhard, Quérat, Gilles, Li, Changqing, Decroly, Etienne, Tas, Ali, Marchand, Arnaud, Chaltin, Patrick, Coutard, Bruno, van Hemert, Martijn, Neyts, Johan, Delang, Leen
Pubblicato in Antimicrob Agents Chemother (2020)

Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors

di Kovacikova, Kristina, Gorostiola González, Marina, Jones, Rhian, Reguera, Juan, Gigante, Alba, Pérez-Pérez, María-Jesús, Pürstinger, Gerhard, Moesslacher, Julia, Langer, Thierry, Jeong, Lak Shin, Delang, Leen, Neyts, Johan, Snijder, Eric J., van Westen, Gerard J. P., van Hemert, Martijn J.
Pubblicato in Antimicrob Agents Chemother (2021)

Design, Synthesis, and Anti-RNA Virus Activity of 6′-Fluorinated-Aristeromycin Analogues

di Yoon, Ji-seong, Kim, Gyudong, Jarhad, Dnyandev B., Kim, Hong-Rae, Shin, Young-Sup, Qu, Shuhao, Sahu, Pramod K., Kim, Hea Ok, Lee, Hyuk Woo, Wang, Su Bin, Kong, Yun Jeong, Chang, Tong-Shin, Ogando, Natacha S., Kovacikova, Kristina, Snijder, Eric J., Posthuma, Clara C., van Hemert, Martijn J., Jeong, Lak Shin
Pubblicato in J Med Chem (2019)