Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors

Chikungunya virus (CHIKV) nonstructural protein 1 (nsP1) harbors the methyltransferase (MTase) and guanylyltransferase (GTase) activities needed for viral RNA capping and represents a promising antiviral drug target. We compared the antiviral efficacies of nsP1 inhibitors belonging to the MADTP, CHV...

全面介紹

Na minha lista:
書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Kovacikova, Kristina, Gorostiola González, Marina, Jones, Rhian, Reguera, Juan, Gigante, Alba, Pérez-Pérez, María-Jesús, Pürstinger, Gerhard, Moesslacher, Julia, Langer, Thierry, Jeong, Lak Shin, Delang, Leen, Neyts, Johan, Snijder, Eric J., van Westen, Gerard J. P., van Hemert, Martijn J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2021
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218635/
https://ncbi.nlm.nih.gov/pubmed/33875421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02566-20
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍