Identification of 2-(4-(Phenylsulfonyl)piperazine-1-yl)pyrimidine Analogues as Novel Inhibitors of Chikungunya Virus

[Image: see text] The chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus, and it is the causative agent of chikungunya fever (CHIKF). Although it has re-emerged as an epidemic threat, so far there are neither vaccines nor pharmacotherapy available to prevent or treat an infection. Herein...

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Publicat a:ACS Med Chem Lett
Autors principals: Moesslacher, Julia, Battisti, Verena, Delang, Leen, Neyts, Johan, Abdelnabi, Rana, Pürstinger, Gerhard, Urban, Ernst, Langer, Thierry
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236252/
https://ncbi.nlm.nih.gov/pubmed/32435404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00662
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