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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Despite the worldwide reemergence of the chikungunya virus (CHIKV) and the high morbidity associated with CHIKV infections, there is no approved vaccine or antiviral treatment available. Here, we aimed to identify the target of a novel class of CHIKV inhibitors, i.e., the CHVB series. CHVB compounds...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Abdelnabi, Rana, Kovacikova, Kristina, Moesslacher, Julia, Donckers, Kim, Battisti, Verena, Leyssen, Pieter, Langer, Thierry, Puerstinger, Gerhard, Quérat, Gilles, Li, Changqing, Decroly, Etienne, Tas, Ali, Marchand, Arnaud, Chaltin, Patrick, Coutard, Bruno, van Hemert, Martijn, Neyts, Johan, Delang, Leen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317993/
https://ncbi.nlm.nih.gov/pubmed/32340991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00649-20
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