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Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery

Despite the worldwide reemergence of the chikungunya virus (CHIKV) and the high morbidity associated with CHIKV infections, there is no approved vaccine or antiviral treatment available. Here, we aimed to identify the target of a novel class of CHIKV inhibitors, i.e., the CHVB series. CHVB compounds...

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Bibliografski detalji
Izdano u:Antimicrob Agents Chemother
Glavni autori: Abdelnabi, Rana, Kovacikova, Kristina, Moesslacher, Julia, Donckers, Kim, Battisti, Verena, Leyssen, Pieter, Langer, Thierry, Puerstinger, Gerhard, Quérat, Gilles, Li, Changqing, Decroly, Etienne, Tas, Ali, Marchand, Arnaud, Chaltin, Patrick, Coutard, Bruno, van Hemert, Martijn, Neyts, Johan, Delang, Leen
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317993/
https://ncbi.nlm.nih.gov/pubmed/32340991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00649-20
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