IMPS-22 FGL2 AS A MULTI-MODALITY REGULATOR OF TUMOR-MEDIATED IMMUNE SUPPRESSION

Por Yan, Jun, Kong, Ling-Yuan, Hu, Jiemiao, Gabrusiewicz, Konrad, Dibra, Denada, Xia, Xueqing, Heimberger, Amy, Li, Shulin
Publicado no Neuro Oncol (2015)

Glioma cancer stem cells induce immunosuppressive macrophages/microglia

Por Wu, Adam, Wei, Jun, Kong, Ling-Yuan, Wang, Yongtao, Priebe, Waldemar, Qiao, Wei, Sawaya, Raymond, Heimberger, Amy B.
Publicado em 2010

FGL2 as a Multimodality Regulator of Tumor-Mediated Immune Suppression and Therapeutic Target in Gliomas

Por Yan, Jun, Kong, Ling-Yuan, Hu, Jiemiao, Gabrusiewicz, Konrad, Dibra, Denada, Xia, Xueqing, Heimberger, Amy B., Li, Shulin
Publicado no J Natl Cancer Inst (2015)

Discovery of cell surface vimentin targeting mAb for direct disruption of GBM tumor initiating cells

Por Noh, Hyangsoon, Yan, Jun, Hong, Sungguan, Kong, Ling-Yuan, Gabrusiewicz, Konrad, Xia, Xueqing, Heimberger, Amy B., Li, Shulin
Publicado no Oncotarget (2016)

Modulating Antiangiogenic Resistance by Inhibiting the Signal Transducer and Activator of Transcription 3 Pathway in Glioblastoma

Por de Groot, John, Liang, Ji, Kong, Ling-Yuan, Wei, Jun, Piao, Yuji, Fuller, Gregory, Qiao, Wei, Heimberger, Amy B.
Publicado em 2012

Hypoxia Potentiates Glioma-Mediated Immunosuppression

Por Wei, Jun, Wu, Adam, Kong, Ling-Yuan, Wang, Yongtao, Fuller, Gregory, Fokt, Isabella, Melillo, Giovanni, Priebe, Waldemar, Heimberger, Amy B.
Publicado em 2011

Activation of a novel Bcr/Abl destruction pathway by WP1130 induces apoptosis of chronic myelogenous leukemia cells

Por Bartholomeusz, Geoffrey A., Talpaz, Moshe, Kapuria, Vaibhav, Kong, Ling Yuan, Wang, Shimei, Estrov, Zeev, Priebe, Waldemar, Wu, Ji, Donato, Nicholas J.
Publicado em 2007

miR-138 exerts anti-glioma efficacy by targeting immune checkpoints

Por Wei, Jun, Nduom, Edjah, Kong, Ling-Yuan, Wang, Fei, Xu, Shuo, Gabrusiewicz, Konrad, Alum, Ali, Fuller, Greg, Calin, George, Heimberger, Amy B
Publicado em 2013

Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immune therapeutic responses

Por Kong, Ling-Yuan, Wu, Adam S., Doucette, Tiffany, Wei, Jun, Priebe, Waldemar, Fuller, Gregory N., Qiao, Wei, Sawaya, Raymond, Rao, Ganesh, Heimberger, Amy B.
Publicado em 2010

Tipping a favorable CNS intratumoral immune response using immune stimulation combined with inhibition of tumor-mediated immune suppression

Por Kong, Ling-Yuan, Wei, Jun, Fuller, Gregory N., Schrand, Brett, Gabrusiewicz, Konrad, Zhou, Shouhao, Rao, Ganesh, Calin, George, Gilboa, Eli, Heimberger, Amy B.
Publicado no Oncoimmunology (2015)

IMPS-34 INNATE IMMUNOLOGICAL COMPENSATORY CONTROL OF GLIOMAGENESIS AND MALIGNANT TRANSFORMATION IN MURINE CD8α KNOCKOUT MODELS

Por Rao, Ganesh, Ling, Xiaoyang, Doucette, Tiffany, Yang, Yuhui, Kong, Ling-Yuan, Wei, Jun, Fuller, Gregory, Nwajei, Felix, Zhou, Shouhao, Caruso, Hillary, Vile, Richard, Heimberger, Amy
Publicado no Neuro Oncol (2015)

Association Between Imatinib-Resistant BCR-ABL Mutation-Negative Leukemia and Persistent Activation of LYN Kinase

Por Wu, Ji, Meng, Feng, Kong, Ling-Yuan, Peng, Zhenghong, Ying, Yunming, Bornmann, William G., Darnay, Bryant G., Lamothe, Betty, Sun, Hanshi, Talpaz, Moshe, Donato, Nicholas J.
Publicado em 2008

The Incidence, Correlation with Tumor Infiltrating Inflammation, and Prognosis of p-STAT3 Expression in Human Gliomas

Por Abou-Ghazal, Mohamed, Yang, David S., Qiao, Wei, Reina-Ortiz, Chantal, Wei, Jun, Kong, Ling-Yuan, Fuller, Gregory N., Hiraoka, Nobuyoshi, Priebe, Waldemar, Sawaya, Raymond, Heimberger, Amy B.
Publicado em 2008

A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells

Por Kong, Ling-Yuan, Wei, Jun, Sharma, Amit K., Barr, Jason, Abou-Ghazal, Mohamed K., Fokt, Izabela, Weinberg, Jeffrey, Rao, Ganesh, Grimm, Elizabeth, Priebe, Waldemar, Heimberger, Amy B.
Publicado em 2008

The tumor microenvironment expression of p-STAT3 influences the efficacy of cyclophosphamide with WP1066 in murine melanoma models

Por Hatiboglu, Mustafa Aziz, Kong, Ling-Yuan, Wei, Jun, Wang, Yongtao, McEnery, Kayla Anne, Fuller, Gregory N., Qiao, Wei, Davies, Michael A., Priebe, Waldemar, Waldemar, Amy B
Publicado em 2011

The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival

Por Lee, Ian, Fox, Patricia S., Ferguson, Sherise D., Bassett, Roland, Kong, Ling-Yuan, Schacherer, Christopher W., Gershenwald, Jeffrey E., Grimm, Elizabeth A., Fuller, Gregory N., Heimberger, Amy B.
Publicado em 2012

Glioma associated cancer-initiating cells induce immune suppression

Por Wei, Jun, Barr, Jason, Kong, Ling-Yuan, Wang, Yongtao, Wu, Adam, Sharma, Amit K., Gumin, Joy, Henry, Verlene, Colman, Howard, Sawaya, Raymond, Lang, Frederick F., Heimberger, Amy B.
Publicado em 2010

Glioma-associated Cytomegalovirus Mediates Subversion of the Monocyte Lineage to a Tumor Propagating Phenotype

Por Dziurzynski, Kristine, Wei, Jun, Qiao, Wei, Hatiboglu, Mustafa Aziz, Kong, Ling-Yuan, Wu, Adam, Wang, Yongtao, Cahill, Daniel, Levine, Nicholas, Prabhu, Sujit, Rao, Ganesh, Sawaya, Raymond, Heimberger, Amy B.
Publicado em 2011

Glioblastoma cancer-initiating cells inhibit T cell proliferation and effector responses by the STAT3 pathway

Por Wei, Jun, Barr, Jason, Kong, Ling-Yuan, Wang, Yongtao, Wu, Adam, Sharma, Amit K., Gumin, Joy, Henry, Verlene, Colman, Howard, Priebe, Waldemar, Sawaya, Raymond, Lang, Frederick F., Heimberger, Amy B.
Publicado em 2010

BMET-14 STAT3 INHIBITION ENHANCES THERAPEUTIC EFFICACY OF RADIATION TREATMENT AGAINST ESTABLISHED BRAIN METASTASIS IN MURINE MELANOMA MODEL

Por Hashimoto, Yuuri, Yaghi, Nasser K., Wei, Jun, Huang, Neal, Ezhilarasan, Ravesanker, Kong, Ling-Yuan, Zhou, Shouhao, Chivukula, Padmanabh, Webb, David C., Priebe, Waldemar, Payne, Joseph E., Sulman, Erik P., Heimberger, Amy B.
Publicado no Neuro Oncol (2015)