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The Expression of p-STAT3 in Stage IV Melanoma: Risk of CNS Metastasis and Survival

PURPOSE: The signal transducer and activator of transcription 3 (STAT3) is a key molecular hub of tumorigenesis and immune suppression. The expression of phosphorylated STAT3 (p-STAT3) has been shown to be higher in melanoma metastasis to the central nervous system (CNS) relative to distant metastas...

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Main Authors: Lee, Ian, Fox, Patricia S., Ferguson, Sherise D., Bassett, Roland, Kong, Ling-Yuan, Schacherer, Christopher W., Gershenwald, Jeffrey E., Grimm, Elizabeth A., Fuller, Gregory N., Heimberger, Amy B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359889/
https://ncbi.nlm.nih.gov/pubmed/22488042
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