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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells

The activation of signal transducer and activator of transcription 3 (STAT3) has been identified as a key mediator that drives the fundamental components of melanoma malignancy, including immune suppression in melanoma patients. Increasing evidence also suggests that regulatory T cells (Tregs) are i...

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Detalhes bibliográficos
Main Authors: Kong, Ling-Yuan, Wei, Jun, Sharma, Amit K., Barr, Jason, Abou-Ghazal, Mohamed K., Fokt, Izabela, Weinberg, Jeffrey, Rao, Ganesh, Grimm, Elizabeth, Priebe, Waldemar, Heimberger, Amy B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674523/
https://ncbi.nlm.nih.gov/pubmed/19002459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0618-y
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