Inhibition of p-STAT3 Enhances IFN-α Efficacy Against Metastatic Melanoma in a Murine Model

PURPOSE: Melanoma is a common and deadly tumor that upon metastasis to the central nervous system (CNS) has a median survival duration of less than 6 months. Activation of the signal transducer and activator of transcription 3 (STAT3) has been identified as a key mediator that drives the fundamental...

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Detalhes bibliográficos
Main Authors: Kong, Ling-Yuan, Gelbard, Alexander, Wei, Jun, Reina-Ortiz, Chantal, Wang, Yongtao, Yang, Eric C., Hailemichael, Yared, Fokt, Izabela, Jayakumar, Arumugam, Qiao, Wei, Fuller, Gregory N., Overwijk, Willem W., Priebe, Waldemar, Heimberger, Amy B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936966/
https://ncbi.nlm.nih.gov/pubmed/20388845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-0279
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