PET Diagnostic Molecules Utilizing Multimeric Cyclic RGD Peptide Analogs for Imaging Integrin α(v)β(3) Receptors

по Liolios, Christos, Sachpekidis, Christos, Kolocouris, Antonios, Dimitrakopoulou-Strauss, Antonia, Bouziotis, Penelope
Опубликовано в: Molecules (2021)

Influence of an Additional Amino Group on the Potency of Aminoadamantanes Against Influenza Virus A. II – Synthesis of Spiropiperazines and In-Vitro Activity Against Influenza A H3...

по Fytas, Christos, Kolocouris, Antonios, Fytas, George, Grigoris, Zoidis, Valmas, Charalambos, Basler, Christopher F.
Опубликовано 2010

The L46P Mutant Confers a Novel Allosteric Mechanism of Resistance Toward the Influenza A Virus M2 S31N Proton Channel Blockers

по Musharrafieh, Rami, Lagarias, Panagiotis I., Ma, Chunlong, Tan, Gene S., Kolocouris, Antonios, Wang, Jun
Опубликовано в: Mol Pharmacol (2019)

Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters

по Thomaston, Jessica L., Polizzi, Nicholas F., Konstantinidi, Athina, Wang, Jun, Kolocouris, Antonios, DeGrado, William F.
Опубликовано в: J Am Chem Soc (2018)

Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments

по Musharrafieh, Rami, Lagarias, Panagiotis, Ma, Chunlong, Hau, Raymond, Romano, Alex, Lambrinidis, George, Kolocouris, Antonios, Wang, Jun
Опубликовано в: ACS Pharmacol Transl Sci (2020)

Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers

по Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Опубликовано в: Res Sq (2020)

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers

по Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Опубликовано в: Nat Struct Mol Biol (2020)

Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors

по Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Опубликовано в: bioRxiv (2020)

Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors

по Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Опубликовано в: ACS Pharmacol Transl Sci (2020)

Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited

по Drakopoulos, Antonios, Tzitzoglaki, Christina, Ma, Chulong, Freudenberger, Kathrin, Hoffmann, Anja, Hu, Yanmei, Gauglitz, Günter, Schmidtke, Michaela, Wang, Jun, Kolocouris, Antonios
Опубликовано в: ACS Med Chem Lett (2017)

X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance

по Thomaston, Jessica L., Konstantinidi, Athina, Liu, Lijun, Lambrinidis, George, Tan, Jingquan, Caffrey, Martin, Wang, Jun, DeGrado, William F., Kolocouris, Antonios
Опубликовано в: Biochemistry (2020)

Pharmacological characterisation of novel adenosine A(3) receptor antagonists

по Barkan, Kerry, Lagarias, Panagiotis, Stampelou, Margarita, Stamatis, Dimitrios, Hoare, Sam, Safitri, Dewi, Klotz, Karl-Norbert, Vrontaki, Eleni, Kolocouris, Antonios, Ladds, Graham
Опубликовано в: Sci Rep (2020)

Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

по Kolocouris, Antonios, Tzitzoglaki, Christina, Johnson, F. Brent, Zell, Roland, Wright, Anna K., Cross, Timothy A., Tietjen, Ian, Fedida, David, Busath, David D.
Опубликовано 2014

Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants

по Drakopoulos, Antonios, Tzitzoglaki, Christina, McGuire, Kelly, Hoffmann, Anja, Konstantinidi, Athina, Kolokouris, Dimitrios, Ma, Chunlong, Freudenberger, Kathrin, Hutterer, Johanna, Gauglitz, Günter, Wang, Jun, Schmidtke, Michaela, Busath, David D., Kolocouris, Antonios
Опубликовано в: ACS Med Chem Lett (2018)

Chemical Probes for Blocking of Influenza A M2 WT and S31N Channels

по Tzitzoglaki, Christina, McGuire, Kelly, Lagarias, Panagiotis, Konstantinidi, Athina, Hoffmann, Anja, Fokina, Natalie A., Ma, Chulong, Papanastasiou, Ioannis P., Schreiner, Peter R., Vázquez, Santiago, Schmidtke, Michaela, Wang, Jun, Busath, David D., Kolocouris, Antonios
Опубликовано в: ACS Chem Biol (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M(pro) and cathepsin L

по Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Опубликовано в: bioRxiv (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M(pro) and cathepsin L

по Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Опубликовано в: Sci Adv (2020)

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

по Ma, Chunlong, Sacco, Michael Dominic, Xia, Zilei, Lambrinidis, George, Townsend, Julia Alma, Hu, Yanmei, Meng, Xiangzhi, Szeto, Tommy, Ba, Mandy, Zhang, Xiujun, Gongora, Maura, Zhang, Fushun, Marty, Michael Thomas, Xiang, Yan, Kolocouris, Antonios, Chen, Yu, Wang, Jun
Опубликовано в: ACS Cent Sci (2021)

Membrane Protein Structure, Function and Dynamics: A Perspective from Experiments and Theory

по Cournia, Zoe, Allen, Toby W., Andricioaei, Ioan, Antonny, Bruno, Baum, Daniel, Brannigan, Grace, Buchete, Nicolae-Viorel, Deckman, Jason T., Delemotte, Lucie, del Val, Coral, Friedman, Ran, Gkeka, Paraskevi, Hege, Hans-Christian, Hénin, Jérôme, Kasimova, Marina A., Kolocouris, Antonios, Klein, Michael L., Khalid, Syma, Lemieux, M. Joanne, Lindow, Norbert, Roy, Mahua, Selent, Jana, Tarek, Mounir, Tofoleanu, Florentina, Vanni, Stefano, Urban, Sinisa, Wales, David J., Smith, Jeremy C., Bondar, Ana-Nicoleta
Опубликовано в: J Membr Biol (2015)