PET Diagnostic Molecules Utilizing Multimeric Cyclic RGD Peptide Analogs for Imaging Integrin α(v)β(3) Receptors

di Liolios, Christos, Sachpekidis, Christos, Kolocouris, Antonios, Dimitrakopoulou-Strauss, Antonia, Bouziotis, Penelope
Pubblicato in Molecules (2021)

Influence of an Additional Amino Group on the Potency of Aminoadamantanes Against Influenza Virus A. II – Synthesis of Spiropiperazines and In-Vitro Activity Against Influenza A H3...

di Fytas, Christos, Kolocouris, Antonios, Fytas, George, Grigoris, Zoidis, Valmas, Charalambos, Basler, Christopher F.
Pubblicazione 2010

The L46P Mutant Confers a Novel Allosteric Mechanism of Resistance Toward the Influenza A Virus M2 S31N Proton Channel Blockers

di Musharrafieh, Rami, Lagarias, Panagiotis I., Ma, Chunlong, Tan, Gene S., Kolocouris, Antonios, Wang, Jun
Pubblicato in Mol Pharmacol (2019)

Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters

di Thomaston, Jessica L., Polizzi, Nicholas F., Konstantinidi, Athina, Wang, Jun, Kolocouris, Antonios, DeGrado, William F.
Pubblicato in J Am Chem Soc (2018)

Investigation of the Drug Resistance Mechanism of M2-S31N Channel Blockers through Biomolecular Simulations and Viral Passage Experiments

di Musharrafieh, Rami, Lagarias, Panagiotis, Ma, Chunlong, Hau, Raymond, Romano, Alex, Lambrinidis, George, Kolocouris, Antonios, Wang, Jun
Pubblicato in ACS Pharmacol Transl Sci (2020)

Structure and Drug Binding of the SARS-CoV-2 Envelope Protein in Phospholipid Bilayers

di Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Pubblicato in Res Sq (2020)

Structure and drug binding of the SARS-CoV-2 envelope protein transmembrane domain in lipid bilayers

di Mandala, Venkata S., McKay, Matthew J., Shcherbakov, Alexander A., Dregni, Aurelio J., Kolocouris, Antonios, Hong, Mei
Pubblicato in Nat Struct Mol Biol (2020)

Ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin are non-specific promiscuous SARS-CoV-2 main protease inhibitors

di Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Pubblicato in bioRxiv (2020)

Ebselen, Disulfiram, Carmofur, PX-12, Tideglusib, and Shikonin Are Nonspecific Promiscuous SARS-CoV-2 Main Protease Inhibitors

di Ma, Chunlong, Hu, Yanmei, Townsend, Julia Alma, Lagarias, Panagiotis I., Marty, Michael Thomas, Kolocouris, Antonios, Wang, Jun
Pubblicato in ACS Pharmacol Transl Sci (2020)

Affinity of Rimantadine Enantiomers against Influenza A/M2 Protein Revisited

di Drakopoulos, Antonios, Tzitzoglaki, Christina, Ma, Chulong, Freudenberger, Kathrin, Hoffmann, Anja, Hu, Yanmei, Gauglitz, Günter, Schmidtke, Michaela, Wang, Jun, Kolocouris, Antonios
Pubblicato in ACS Med Chem Lett (2017)

X-ray crystal structures of the influenza M2 proton channel drug-resistant V27A mutant bound to a spiro-adamantyl amine inhibitor reveal the mechanism of adamantane resistance

di Thomaston, Jessica L., Konstantinidi, Athina, Liu, Lijun, Lambrinidis, George, Tan, Jingquan, Caffrey, Martin, Wang, Jun, DeGrado, William F., Kolocouris, Antonios
Pubblicato in Biochemistry (2020)

Pharmacological characterisation of novel adenosine A(3) receptor antagonists

di Barkan, Kerry, Lagarias, Panagiotis, Stampelou, Margarita, Stamatis, Dimitrios, Hoare, Sam, Safitri, Dewi, Klotz, Karl-Norbert, Vrontaki, Eleni, Kolocouris, Antonios, Ladds, Graham
Pubblicato in Sci Rep (2020)

Aminoadamantanes with Persistent in Vitro Efficacy against H1N1 (2009) Influenza A

di Kolocouris, Antonios, Tzitzoglaki, Christina, Johnson, F. Brent, Zell, Roland, Wright, Anna K., Cross, Timothy A., Tietjen, Ian, Fedida, David, Busath, David D.
Pubblicazione 2014

Unraveling the Binding, Proton Blockage, and Inhibition of Influenza M2 WT and S31N by Rimantadine Variants

di Drakopoulos, Antonios, Tzitzoglaki, Christina, McGuire, Kelly, Hoffmann, Anja, Konstantinidi, Athina, Kolokouris, Dimitrios, Ma, Chunlong, Freudenberger, Kathrin, Hutterer, Johanna, Gauglitz, Günter, Wang, Jun, Schmidtke, Michaela, Busath, David D., Kolocouris, Antonios
Pubblicato in ACS Med Chem Lett (2018)

Chemical Probes for Blocking of Influenza A M2 WT and S31N Channels

di Tzitzoglaki, Christina, McGuire, Kelly, Lagarias, Panagiotis, Konstantinidi, Athina, Hoffmann, Anja, Fokina, Natalie A., Ma, Chulong, Papanastasiou, Ioannis P., Schreiner, Peter R., Vázquez, Santiago, Schmidtke, Michaela, Wang, Jun, Busath, David D., Kolocouris, Antonios
Pubblicato in ACS Chem Biol (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveals strategy for developing dual inhibitors against M(pro) and cathepsin L

di Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Pubblicato in bioRxiv (2020)

Structure and inhibition of the SARS-CoV-2 main protease reveal strategy for developing dual inhibitors against M(pro) and cathepsin L

di Sacco, Michael Dominic, Ma, Chunlong, Lagarias, Panagiotis, Gao, Ang, Townsend, Julia Alma, Meng, Xiangzhi, Dube, Peter, Zhang, Xiujun, Hu, Yanmei, Kitamura, Naoya, Hurst, Brett, Tarbet, Bart, Marty, Michael Thomas, Kolocouris, Antonios, Xiang, Yan, Chen, Yu, Wang, Jun
Pubblicato in Sci Adv (2020)

Discovery of SARS-CoV-2 Papain-like Protease Inhibitors through a Combination of High-Throughput Screening and a FlipGFP-Based Reporter Assay

di Ma, Chunlong, Sacco, Michael Dominic, Xia, Zilei, Lambrinidis, George, Townsend, Julia Alma, Hu, Yanmei, Meng, Xiangzhi, Szeto, Tommy, Ba, Mandy, Zhang, Xiujun, Gongora, Maura, Zhang, Fushun, Marty, Michael Thomas, Xiang, Yan, Kolocouris, Antonios, Chen, Yu, Wang, Jun
Pubblicato in ACS Cent Sci (2021)

Membrane Protein Structure, Function and Dynamics: A Perspective from Experiments and Theory

di Cournia, Zoe, Allen, Toby W., Andricioaei, Ioan, Antonny, Bruno, Baum, Daniel, Brannigan, Grace, Buchete, Nicolae-Viorel, Deckman, Jason T., Delemotte, Lucie, del Val, Coral, Friedman, Ran, Gkeka, Paraskevi, Hege, Hans-Christian, Hénin, Jérôme, Kasimova, Marina A., Kolocouris, Antonios, Klein, Michael L., Khalid, Syma, Lemieux, M. Joanne, Lindow, Norbert, Roy, Mahua, Selent, Jana, Tarek, Mounir, Tofoleanu, Florentina, Vanni, Stefano, Urban, Sinisa, Wales, David J., Smith, Jeremy C., Bondar, Ana-Nicoleta
Pubblicato in J Membr Biol (2015)