Ex Vivo Generation of Human Alloantigen-Specific Regulatory T Cells from CD4(pos)CD25(high) T Cells for Immunotherapy

Por Peters, Jorieke H., Hilbrands, Luuk B., Koenen, Hans J. P. M., Joosten, Irma
Publicado em 2008

An Autocrine TNFα–Tumor Necrosis Factor Receptor 2 Loop Promotes Epigenetic Effects Inducing Human Treg Stability In Vitro

Por Urbano, Paulo C. M., Koenen, Hans J. P. M., Joosten, Irma, He, Xuehui
Publicado no Front Immunol (2018)

Metabolic Pathways Involved in Regulatory T Cell Functionality

Por Kempkes, Rosalie W. M., Joosten, Irma, Koenen, Hans J. P. M., He, Xuehui
Publicado no Front Immunol (2019)

Immunological Monitoring of Renal Transplant Recipients to Predict Acute Allograft Rejection Following the Discontinuation of Tacrolimus

Por Kreijveld, Ellen, Koenen, Hans J. P. M., van Cranenbroek, Bram, van Rijssen, Esther, Joosten, Irma, Hilbrands, Luuk B.
Publicado em 2008

Clinical Grade Treg: GMP Isolation, Improvement of Purity by CD127(pos) Depletion, Treg Expansion, and Treg Cryopreservation

Por Peters, Jorieke H., Preijers, Frank W., Woestenenk, Rob, Hilbrands, Luuk B., Koenen, Hans J. P. M., Joosten, Irma
Publicado em 2008

COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients

Por Kox, Matthijs, Frenzel, Tim, Schouten, Jeroen, van de Veerdonk, Frank L., Koenen, Hans J. P. M., Pickkers, Peter
Publicado no Crit Care (2020)

A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells

Por He, Xuehui, Landman, Sija, Bauland, Stijn C. G., van den Dolder, Juliette, Koenen, Hans J. P. M., Joosten, Irma
Publicado no PLoS One (2016)

Single CD28 stimulation induces stable and polyclonal expansion of human regulatory T cells

Por He, Xuehui, Smeets, Ruben L., van Rijssen, Esther, Boots, Annemieke M. H., Joosten, Irma, Koenen, Hans J. P. M.
Publicado no Sci Rep (2017)

Immune responses to azacytidine in animal models of inflammatory disorders: a systematic review

Por Landman, Sija, van der Horst, Chiel, van Erp, Piet E. J., Joosten, Irma, de Vries, Rob, Koenen, Hans J. P. M.
Publicado no J Transl Med (2021)

Longitudinal Analysis of T and B Cell Phenotype and Function in Renal Transplant Recipients with or without Rituximab Induction Therapy

Por Kamburova, Elena G., Koenen, Hans J. P. M., van den Hoogen, Martijn W. F., Baas, Marije C., Joosten, Irma, Hilbrands, Luuk B.
Publicado no PLoS One (2014)

Intradermal injection of low dose human regulatory T cells inhibits skin inflammation in a humanized mouse model

Por Landman, Sija, de Oliveira, Vivian L., van Erp, Piet E. J., Fasse, Esther, Bauland, Stijn C. G., Joosten, Irma, Koenen, Hans J. P. M.
Publicado no Sci Rep (2018)

TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression

Por Urbano, Paulo C. M., He, Xuehui, van Heeswijk, Bennie, Filho, Omar P. S., Tijssen, Henk, Smeets, Ruben L., Joosten, Irma, Koenen, Hans J. P. M.
Publicado no Front Immunol (2020)

DNA Methyltransferase Inhibition Promotes Th1 Polarization in Human CD4(+)CD25(high) FOXP3(+) Regulatory T Cells but Does Not Affect Their Suppressive Capacity

Por Landman, Sija, Cruijsen, Marjan, Urbano, Paulo C. M., Huls, Gerwin, van Erp, Piet E. J., van Rijssen, Esther, Joosten, Irma, Koenen, Hans J. P. M.
Publicado no J Immunol Res (2018)

1,25-dihydroxyvitamin D(3) Modulates Cytokine Production Induced by Candida albicans: Impact of Seasonal Variation of Immune Responses

Por Khoo, Ai-Leng, Chai, Louis Y.A., Koenen, Hans J.P.M., Kullberg, Bart-Jan, Joosten, Irma, van der Ven, André J.A.M., Netea, Mihai G.
Publicado em 2011

Seasonal Variation in Vitamin D(3) Levels Is Paralleled by Changes in the Peripheral Blood Human T Cell Compartment

Por Khoo, Ai-Leng, Koenen, Hans J. P. M., Chai, Louis Y. A., Sweep, Fred C. G. J., Netea, Mihai G., van der Ven, André J. A. M., Joosten, Irma
Publicado em 2012

1,25-Dihydroxyvitamin D(3) inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells

Por Khoo, Ai-Leng, Joosten, Irma, Michels, Meta, Woestenenk, Rob, Preijers, Frank, He, Xue-Hui, Netea, Mihai G, van der Ven, André J A M, Koenen, Hans J P M
Publicado em 2011

Synthetic Extracellular Matrices as a Toolbox to Tune Stem Cell Secretome

Por Liu, Kaizheng, Veenendaal, Tomas, Wiendels, Maury, Ruiz-Zapata, Alejandra M., van Laar, Justin, Kyranas, Rafail, Enting, Hilde, van Cranenbroek, Bram, Koenen, Hans J. P. M., Mihaila, Silvia M., Oosterwijk, Egbert, Kouwer, Paul H. J.
Publicado no ACS Appl Mater Interfaces (2020)

The role of interleukin-1 beta in the pathophysiology of Schnitzler’s syndrome

Por de Koning, Heleen D., Schalkwijk, Joost, Stoffels, Monique, Jongekrijg, Johanna, Jacobs, Joannes F. M., Verwiel, Eugène, Koenen, Hans J. P. M., Preijers, Frank, Holzinger, Dirk, Joosten, Irma, van der Meer, Jos W. M., Simon, Anna
Publicado no Arthritis Res Ther (2015)

Persistent Systemic Inflammation in Patients With Severe Burn Injury Is Accompanied by Influx of Immature Neutrophils and Shifts in T Cell Subsets and Cytokine Profiles

Por Mulder, Patrick P. G., Vlig, Marcel, Boekema, Bouke K. H. L., Stoop, Matthea M., Pijpe, Anouk, van Zuijlen, Paul P. M., de Jong, Evelien, van Cranenbroek, Bram, Joosten, Irma, Koenen, Hans J. P. M., Ulrich, Magda M. W.
Publicado no Front Immunol (2021)

Humanized Mouse Model of Skin Inflammation Is Characterized by Disturbed Keratinocyte Differentiation and Influx of IL-17A Producing T Cells

Por de Oliveira, Vivian L., Keijsers, Romy R. M. C., van de Kerkhof, Peter C. M., Seyger, Marieke M. B., Fasse, Esther, Svensson, Lars, Latta, Markus, Norsgaard, Hanne, Labuda, Tord, Hupkens, Pieter, van Erp, Piet E. J., Joosten, Irma, Koenen, Hans J. P. M.
Publicado em 2012