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TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression
Maintenance of regulatory T cells CD4(+)CD25(high)FOXP3(+) (Treg) stability is vital for proper Treg function and controlling the immune equilibrium. Treg cells are heterogeneous and can reveal plasticity, exemplified by their potential to express IL-17A. TNFα-TNFR2 signaling controls IL-17A express...
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| Publicado no: | Front Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986271/ https://ncbi.nlm.nih.gov/pubmed/32038615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03047 |
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