Discovery and Development of Anti-HIV Therapeutic Agents: Progress Towards Improved HIV Medication

door Maeda, Kenji, Das, Debananda, Kobayakawa, Takuya, Tamamura, Hirokazu, Takeuchi, Hiroaki
Gepubliceerd in Curr Top Med Chem (2019)

Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application

door Kobayakawa, Takuya, Matsuzaki, Yudai, Hozumi, Kentaro, Nomura, Wataru, Nomizu, Motoyoshi, Tamamura, Hirokazu
Gepubliceerd in ACS Med Chem Lett (2017)

Synthesis and Evaluation of Dimeric Derivatives of Diacylglycerol–Lactones as Protein Kinase C Ligands

door Ohashi, Nami, Kobayashi, Ryosuke, Nomura, Wataru, Kobayakawa, Takuya, Czikora, Agnes, Herold, Brienna K., Lewin, Nancy E., Blumberg, Peter M., Tamamura, Hirokazu
Gepubliceerd in Bioconjug Chem (2017)

Benzolactam-related compounds promote apoptosis of HIV-infected human cells via protein kinase C–induced HIV latency reversal

door Matsuda, Kouki, Kobayakawa, Takuya, Tsuchiya, Kiyoto, Hattori, Shin-ichiro, Nomura, Wataru, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Oka, Shinichi, Endo, Yasuyuki, Tamamura, Hirokazu, Mitsuya, Hiroaki, Maeda, Kenji
Gepubliceerd in J Biol Chem (2019)

Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins

door Kobayakawa, Takuya, Yokoyama, Masaru, Tsuji, Kohei, Fujino, Masayuki, Kurakami, Masaki, Boku, Sayaka, Nakayama, Miyuki, Kaneko, Moemi, Ohashi, Nami, Kotani, Osamu, Murakami, Tsutomu, Sato, Hironori, Tamamura, Hirokazu
Gepubliceerd in Biomolecules (2021)

A Therapeutic Strategy to Combat HIV-1 Latently Infected Cells With a Combination of Latency-Reversing Agents Containing DAG-Lactone PKC Activators

door Matsuda, Kouki, Kobayakawa, Takuya, Kariya, Ryusho, Tsuchiya, Kiyoto, Ryu, Shoraku, Tsuji, Kohei, Ishii, Takahiro, Gatanaga, Hiroyuki, Yoshimura, Kazuhisa, Okada, Seiji, Hamada, Akinobu, Mitsuya, Hiroaki, Tamamura, Hirokazu, Maeda, Kenji
Gepubliceerd in Front Microbiol (2021)