Evidence for Heterozygous Abnormalities of the Elastin Gene (ELN) Affecting the Quantity of Vocal Fold Elastic Fibers: A Pilot Study

Por Watts, Christopher R., Knutsen, Russell H., Ciliberto, Christopher, Mecham, Robert P.
Publicado em 2010

Albumin contributes to kidney disease progression in Alport syndrome

Por Jarad, George, Knutsen, Russell H., Mecham, Robert P., Miner, Jeffrey H.
Publicado no Am J Physiol Renal Physiol (2016)

Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice

Por Le, Victoria P., Knutsen, Russell H., Mecham, Robert P., Wagenseil, Jessica E.
Publicado em 2011

Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure

Por Shifren, Adrian, Durmowicz, Anthony G., Knutsen, Russell H., Faury, Gilles, Mecham, Robert P.
Publicado em 2008

Reduced Vessel Elasticity Alters Cardiovascular Structure and Function in Newborn Mice

Por Wagenseil, Jessica E., Ciliberto, Chris H., Knutsen, Russell H., Levy, Marilyn A., Kovacs, Attila, Mecham, Robert P.
Publicado em 2009

The importance of elastin to aortic development in mice

Por Wagenseil, Jessica E., Ciliberto, Christopher H., Knutsen, Russell H., Levy, Marilyn A., Kovacs, Attila, Mecham, Robert P.
Publicado em 2010

Genetic Modifiers of Cardiovascular Phenotype Caused by Elastin Haploinsufficiency Act by Extrinsic Noncomplementation

Por Kozel, Beth A., Knutsen, Russell H., Ye, Li, Ciliberto, Christopher H., Broekelmann, Thomas J., Mecham, Robert P.
Publicado em 2011

Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice

Por Ma, Xiucui, Tittiger, Mindy, Knutsen, Russell H., Kovacs, Attila, Schaller, Laura, Mecham, Robert P., Ponder, Katherine P.
Publicado em 2008

Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness

Por Halabi, Carmen M., Broekelmann, Thomas J., Knutsen, Russell H., Ye, Li, Mecham, Robert P., Kozel, Beth A.
Publicado no Am J Physiol Heart Circ Physiol (2015)

Altered reactivity of resistance vasculature contributes to hypertension in elastin insufficiency

Por Osei-Owusu, Patrick, Knutsen, Russell H., Kozel, Beth A., Dietrich, Hans H., Blumer, Kendall J., Mecham, Robert P.
Publicado em 2014

Deficiency in Microfibril-associated Glycoprotein-1 Leads to Complex Phenotypes in Multiple Organ Systems

Por Weinbaum, Justin S., Broekelmann, Thomas J., Pierce, Richard A., Werneck, Claudio C., Segade, Fernando, Craft, Clarissa S., Knutsen, Russell H., Mecham, Robert P.
Publicado em 2008

Skin Findings in Williams Syndrome

Por Kozel, Beth A., Bayliss, Susan J., Berk, David R., Waxler, Jessica L, Knutsen, Russell H., Danback, Joshua R., Pober, Barbara R.
Publicado em 2014

Discrete contributions of elastic fiber components to arterial development and mechanical compliance

Por Carta, Luca, Wagenseil, Jessica E., Knutsen, Russell H., Mariko, Boubacar, Faury, Gilles, Davis, Elaine C., Starcher, Barry, Mecham, Robert P., Ramirez, Francesco
Publicado em 2009

WILLIAMS SYNDROME PREDISPOSES TO VASCULAR STIFFNESS MODIFIED BY ANTI-HYPERTENSIVE USE AND COPY NUMBER CHANGES IN NCF1

Por Kozel, Beth A., Danback, Joshua, Waxler, Jessica, Knutsen, Russell H., Fuentes, Lisa de las, Reusz, Gyorgy S., Kis, Eva, Bhatt, Ami, Pober, Barbara R
Publicado em 2013

An afferent vagal nerve pathway links hepatic PPARα activation to glucocorticoid-induced insulin resistance and hypertension

Por Bernal-Mizrachi, Carlos, Xiaozhong, Liu, Yin, Li, Knutsen, Russell H., Howard, Michael J., Arends, Joop J. A., DeSantis, Pascual, Coleman, Trey, Semenkovich, Clay F.
Publicado em 2007

Pathogenesis of aortic dilatation in mucopolysaccharidosis VII mice may involve complement activation

Por Baldo, Guilherme, Wu, Susan, Howe, Ruth A., Ramamoothy, Meera, Knutsen, Russell H., Fang, Jiali, Mecham, Robert P., Liu, Yuli, Wu, Xiaobo, Atkinson, John P., Ponder, Katherine P.
Publicado em 2011

MECHANISMS OF EMPHYSEMA IN AUTOSOMAL DOMINANT CUTIS LAXA

Por Hu, Qirui, Shifren, Adrian, Sens, Carla, Choi, Jiwon, Szabo, Zoltan, Starcher, Barry C., Knutsen, Russell H., Shipley, J. Michael, Davis, Elaine C., Mecham, Robert P., Urban, Zsolt
Publicado em 2010

Alternative Splicing and Tissue-specific Elastin Misassembly Act as Biological Modifiers of Human Elastin Gene Frameshift Mutations Associated with Dominant Cutis Laxa

Por Sugitani, Hideki, Hirano, Eiichi, Knutsen, Russell H., Shifren, Adrian, Wagenseil, Jessica E., Ciliberto, Christopher, Kozel, Beth A., Urban, Zsolt, Davis, Elaine C., Broekelmann, Thomas J., Mecham, Robert P.
Publicado em 2012

Microfibril-associated Glycoprotein 2 (MAGP2) Loss of Function Has Pleiotropic Effects in Vivo

Por Combs, Michelle D., Knutsen, Russell H., Broekelmann, Thomas J., Toennies, Holly M., Brett, Thomas J., Miller, Chantel A., Kober, Daniel L., Craft, Clarissa S., Atkinson, Jeffrey J., Shipley, J. Michael, Trask, Barbara C., Mecham, Robert P.
Publicado em 2013

Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency

Por Faury, Gilles, Pezet, Mylène, Knutsen, Russell H., Boyle, Walter A., Heximer, Scott P., McLean, Sean E., Minkes, Robert K., Blumer, Kendall J., Kovacs, Attila, Kelly, Daniel P., Li, Dean Y., Starcher, Barry, Mecham, Robert P.
Publicado em 2003