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Elastin insufficiency predisposes to elevated pulmonary circulatory pressures through changes in elastic artery structure
Elastin is a major structural component of large elastic arteries and a principal determinant of arterial biomechanical properties. Elastin loss-of-function mutations in humans have been linked to the autosomal-dominant disease supravalvular aortic stenosis, which is characterized by stenotic lesion...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584846/ https://ncbi.nlm.nih.gov/pubmed/18772328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.90563.2008 |
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