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Albumin contributes to kidney disease progression in Alport syndrome

Alport syndrome is a familial kidney disease caused by defects in the collagen type IV network of the glomerular basement membrane. Lack of collagen-α(3)α(4)α(5)(IV) changes the glomerular basement membrane morphologically and functionally, rendering it leaky to albumin and other plasma proteins. Fi...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Jarad, George, Knutsen, Russell H., Mecham, Robert P., Miner, Jeffrey H.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967167/
https://ncbi.nlm.nih.gov/pubmed/27147675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00456.2015
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