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Synaptopodin deficiency exacerbates kidney disease in a mouse model of Alport syndrome
Synaptopodin (Synpo) is an actin-associated protein in podocyte foot processes. By generating mice that completely lack Synpo, we previously showed that Synpo is dispensable for normal kidney function. However, lack of Synpo worsened adriamycin-induced nephropathy, indicating a protective role for S...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8321802/ https://ncbi.nlm.nih.gov/pubmed/34029143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00035.2021 |
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