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Synaptopodin Is Dispensable for Normal Podocyte Homeostasis but Is Protective in the Context of Acute Podocyte Injury

BACKGROUND: Synaptopodin (Synpo) is an actin-associated protein in podocytes and dendritic spines. Many functions in regulating the actin cytoskeleton via RhoA and other pathways have been ascribed to Synpo, yet no pathogenic mutations in the SYNPO gene have been discovered in patients. Naturally oc...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Ning, Liang, Suleiman, Hani Y., Miner, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790210/
https://ncbi.nlm.nih.gov/pubmed/32938649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050572
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