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Synaptopodin Is Dispensable for Normal Podocyte Homeostasis but Is Protective in the Context of Acute Podocyte Injury

BACKGROUND: Synaptopodin (Synpo) is an actin-associated protein in podocytes and dendritic spines. Many functions in regulating the actin cytoskeleton via RhoA and other pathways have been ascribed to Synpo, yet no pathogenic mutations in the SYNPO gene have been discovered in patients. Naturally oc...

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Bibliografiske detaljer
Udgivet i:J Am Soc Nephrol
Main Authors: Ning, Liang, Suleiman, Hani Y., Miner, Jeffrey H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7790210/
https://ncbi.nlm.nih.gov/pubmed/32938649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050572
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