Novel Therapeutic Targets of Tumor Metabolism

Por Kishton, Rigel J., Rathmell, Jeffrey C.
Publicado no Cancer J (2015)

Metabolic regulation of T cell longevity and function in tumor immunotherapy

Por Kishton, Rigel J., Sukumar, Madhusudhanan, Restifo, Nicholas P
Publicado no Cell Metab (2017)

A guide to immunometabolism for immunologists

Por O’Neill, Luke A. J., Kishton, Rigel J., Rathmell, Jeff
Publicado no Nat Rev Immunol (2016)

Metabolic stress is a barrier to Epstein–Barr virus-mediated B-cell immortalization

Por McFadden, Karyn, Hafez, Amy Y., Kishton, Rigel, Messinger, Joshua E., Nikitin, Pavel A., Rathmell, Jeffrey C., Luftig, Micah A.
Publicado no Proc Natl Acad Sci U S A (2016)

Leptin Directly Promotes T Cell Glycolytic Metabolism to Drive Effector T cell Differentiation in Autoimmunity

Por Gerriets, Valerie A., Danzaki, Keiko, Kishton, Rigel J., Eisner, William, Nichols, Amanda G., Saucillo, Donte C., Shinohara, Mari L., MacIver, Nancie J.
Publicado no Eur J Immunol (2016)

Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia

Por Siska, Peter J., van der Windt, Gerritje J. W., Kishton, Rigel J., Cohen, Sivan, Eisner, William, MacIver, Nancie J., Kater, Arnon P., Weinberg, J. Brice, Rathmell, Jeffrey C.
Publicado no J Immunol (2016)

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation

Por Zeng, Hu, Cohen, Sivan, Guy, Cliff, Shrestha, Sharad, Neale, Geoffrey, Brown, Scott A., Cloer, Caryn, Kishton, Rigel J., Gao, Xia, Youngblood, Ben, Do, Mytrang, Li, Ming O., Locasale, Jason W., Rathmell, Jeffrey C., Chi, Hongbo
Publicado no Immunity (2016)

Foxp3 and Toll-like receptor signaling balance T(reg) cell anabolic metabolism for suppression

Por Gerriets, Valerie A, Kishton, Rigel J, Johnson, Marc O, Cohen, Sivan, Siska, Peter J, Nichols, Amanda G, Warmoes, Marc O, de Cubas, Aguirre A, MacIver, Nancie J, Locasale, Jason W, Turka, Laurence A, Wells, Andrew D, Rathmell, Jeffrey C
Publicado no Nat Immunol (2016)

AMPK is essential to balance glycolysis and mitochondrial metabolism to control T-ALL cell stress and survival

Por Kishton, Rigel J., Barnes, Carson E., Nichols, Amanda G., Cohen, Sivan, Gerriets, Valerie A., Siska, Peter J., Macintyre, Andrew N., Goraksha-Hicks, Pankuri, de Cubas, Aguirre A., Liu, Tingyu, Warmoes, Marc O., Abel, E. Dale, Yeoh, Allen Eng Juh, Gershon, Timothy R., Rathmell, W. Kimryn, Richards, Kristy L., Locasale, Jason W., Rathmell, Jeffrey C.
Publicado no Cell Metab (2016)

Metabolic programming and PDHK1 control CD4(+) T cell subsets and inflammation

Por Gerriets, Valerie A., Kishton, Rigel J., Nichols, Amanda G., Macintyre, Andrew N., Inoue, Makoto, Ilkayeva, Olga, Winter, Peter S., Liu, Xiaojing, Priyadharshini, Bhavana, Slawinska, Marta E., Haeberli, Lea, Huck, Catherine, Turka, Laurence A., Wood, Kris C., Hale, Laura P., Smith, Paul A., Schneider, Martin A., MacIver, Nancie J., Locasale, Jason W., Newgard, Christopher B., Shinohara, Mari L., Rathmell, Jeffrey C.
Publicado no J Clin Invest (2014)