Metabolic stress is a barrier to Epstein–Barr virus-mediated B-cell immortalization

Epstein–Barr virus (EBV) is an oncogenic herpesvirus that has been causally linked to the development of B-cell and epithelial malignancies. Early after infection, EBV induces a transient period of hyperproliferation that is suppressed by the activation of the DNA damage response and a G1/S-phase gr...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: McFadden, Karyn, Hafez, Amy Y., Kishton, Rigel, Messinger, Joshua E., Nikitin, Pavel A., Rathmell, Jeffrey C., Luftig, Micah A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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PNAS Plus
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760815/
https://ncbi.nlm.nih.gov/pubmed/26802124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517141113
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