Limited nucleotide pools restrict Epstein–Barr virus-mediated B-cell immortalization

Activation of cellular oncogenes as well as infection with tumor viruses can promote aberrant proliferation and activation of the host DNA damage response. Epstein–Barr virus (EBV) infection of primary human B cells induces a transient period of hyper-proliferation, but many of these infected cells...

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Publicat a:Oncogenesis
Autors principals: Hafez, A Y, Messinger, J E, McFadden, K, Fenyofalvi, G, Shepard, C N, Lenzi, G M, Kim, B, Luftig, M A
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519195/
https://ncbi.nlm.nih.gov/pubmed/28604764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.46
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