Limited nucleotide pools restrict Epstein–Barr virus-mediated B-cell immortalization

Activation of cellular oncogenes as well as infection with tumor viruses can promote aberrant proliferation and activation of the host DNA damage response. Epstein–Barr virus (EBV) infection of primary human B cells induces a transient period of hyper-proliferation, but many of these infected cells...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Hafez, A Y, Messinger, J E, McFadden, K, Fenyofalvi, G, Shepard, C N, Lenzi, G M, Kim, B, Luftig, M A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519195/
https://ncbi.nlm.nih.gov/pubmed/28604764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.46
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