Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis

Por Dong, Wentao, Keibler, Mark A., Stephanopoulos, Gregory
Publicado no Metab Eng (2017)

Expanding the Concepts and Tools of Metabolic Engineering to Elucidate Cancer Metabolism

Por Keibler, Mark A., Fendt, Sarah-Maria, Stephanopoulos, Gregory
Publicado em 2012

Quantifying the demand for central carbon metabolism precursors for biosynthesis in proliferating cells

Por Keibler, Mark, Wasylenko, Thomas, Kelleher, Joanne, Stephanopoulos, Gregory
Publicado em 2014

(13)C Isotope-Assisted Methods for Quantifying Glutamine Metabolism in Cancer Cells

Por Zhang, Jie, Ahn, Woo Suk, Gameiro, Paulo A., Keibler, Mark A., Zhang, Zhe, Stephanopoulos, Gregory
Publicado no Methods Enzymol (2014)

Metabolic requirements for cancer cell proliferation

Por Keibler, Mark A., Wasylenko, Thomas M., Kelleher, Joanne K., Iliopoulos, Othon, Vander Heiden, Matthew G., Stephanopoulos, Gregory
Publicado no Cancer Metab (2016)

Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation

Por Berrios, Christian, Padi, Megha, Keibler, Mark A., Park, Donglim Esther, Molla, Vadim, Cheng, Jingwei, Lee, Soo Mi, Stephanopoulos, Gregory, Quackenbush, John, DeCaprio, James A.
Publicado no PLoS Pathog (2016)

Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

Por Fendt, Sarah-Maria, Bell, Eric L., Keibler, Mark A., Olenchock, Benjamin A., Mayers, Jared R., Wasylenko, Thomas M., Vokes, Natalie I., Guarente, Leonard, Vander Heiden, Matthew G., Stephanopoulos, Gregory
Publicado em 2013

Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells

Por Hung, Yin P, Teragawa, Carolyn, Kosaisawe, Nont, Gillies, Taryn E, Pargett, Michael, Minguet, Marta, Distor, Kevin, Rocha-Gregg, Briana L, Coloff, Jonathan L, Keibler, Mark A, Stephanopoulos, Gregory, Yellen, Gary, Brugge, Joan S, Albeck, John G
Publicado no eLife (2017)

The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival

Por Wang, Haizhen, Nicolay, Brandon N., Chick, Joel M., Gao, Xueliang, Geng, Yan, Ren, Hong, Gao, Hui, Yang, Guizhi, Williams, Juliet A., Suski, Jan M., Keibler, Mark A., Sicinska, Ewa, Gerdemann, Ulrike, Haining, W. Nicholas, Roberts, Thomas M., Polyak, Kornelia, Gygi, Steven P., Dyson, Nicholas J., Sicinski, Piotr
Publicado no Nature (2017)

Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism

Por Fendt, Sarah-Maria, Bell, Eric L., Keibler, Mark A., Davidson, Shawn M., Wirth, Gregory J., Fiske, Brian, Mayers, Jared R., Schwab, Matthias, Bellinger, Gary, Csibi, Alfredo, Patnaik, Akash, Jose Blouin, Marie, Cantley, Lewis C., Guarente, Leonard, Blenis, John, Pollak, Michael N., Olumi, Aria F., Vander Heiden, Matthew G., Stephanopoulos, Gregory
Publicado em 2013

Direct evidence for cancer cell-autonomous extracellular protein catabolism in pancreatic tumors

Por Davidson, Shawn M., Jonas, Oliver, Keibler, Mark A., Hou, Han Wei, Luengo, Alba, Mayers, Jared R., Wyckoff, Jeffrey, Del Rosario, Amanda, Whitman, Matthew, Chin, Christopher R., Condon, Kendall J., Lammers, Alex, Kellersberger, Katherine A., Stall, Brian J., Stephanopoulos, Gregory, Bar-Sagi, Dafna, Han, Jongyoon, Rabinowitz, Joshua D., Cima, Michael, Langer, Robert, Vander Heiden, Matthew G.
Publicado no Nat Med (2016)

Environment impacts the metabolic dependencies of Ras-driven non-small cell lung cancer

Por Davidson, Shawn M., Papagiannakopoulos, Thales, Olenchock, Benjamin A., Heyman, Julia E., Keibler, Mark A., Luengo, Alba, Bauer, Matthew R., Jha, Abhishek K., O’Brien, James P., Pierce, Kerry A., Gui, Dan Y., Sullivan, Lucas B., Wasylenko, Thomas M., Subbaraj, Lakshmipriya, Chin, Christopher R., Stephanopolous, Gregory, Mott, Bryan T., Jacks, Tyler, Clish, Clary B., Vander Heiden, Matthew G.
Publicado no Cell Metab (2016)