Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation

Merkel cell polyomavirus (MCPyV) is an etiological agent of Merkel cell carcinoma (MCC), a highly aggressive skin cancer. The MCPyV small tumor antigen (ST) is required for maintenance of MCC and can transform normal cells. To gain insight into cellular perturbations induced by MCPyV ST, we performe...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Berrios, Christian, Padi, Megha, Keibler, Mark A., Park, Donglim Esther, Molla, Vadim, Cheng, Jingwei, Lee, Soo Mi, Stephanopoulos, Gregory, Quackenbush, John, DeCaprio, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5120958/
https://ncbi.nlm.nih.gov/pubmed/27880818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006020
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