Identification of Natural Compounds against Neurodegenerative Diseases Using In Silico Techniques

av Ivanova, Larisa, Karelson, Mati, Dobchev, Dimitar A.
I publikationen Molecules (2018)

Multitarget Approach to Drug Candidates against Alzheimer’s Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets

av Ivanova, Larisa, Karelson, Mati, Dobchev, Dimitar A.
I publikationen Molecules (2020)

Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors

av Selberg, Simona, Seli, Neinar, Kankuri, Esko, Karelson, Mati
I publikationen ACS Omega (2021)

Small-Molecule Ligands as Potential GDNF Family Receptor Agonists

av Ivanova, Larisa, Tammiku-Taul, Jaana, Sidorova, Yulia, Saarma, Mart, Karelson, Mati
I publikationen ACS Omega (2018)

1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors

av Ivanova, Larisa, Rausalu, Kai, Žusinaite, Eva, Tammiku-Taul, Jaana, Merits, Andres, Karelson, Mati
I publikationen ACS Omega (2021)

Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands

av Ivanova, Larisa, Tammiku-Taul, Jaana, García-Sosa, Alfonso T., Sidorova, Yulia, Saarma, Mart, Karelson, Mati
I publikationen ACS Omega (2018)

HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators

av Selberg, Simona, Žusinaite, Eva, Herodes, Koit, Seli, Neinar, Kankuri, Esko, Merits, Andres, Karelson, Mati
I publikationen ACS Omega (2021)

Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons

av Selberg, Simona, Yu, Li-Ying, Bondarenko, Olesja, Kankuri, Esko, Seli, Neinar, Kovaleva, Vera, Herodes, Koit, Saarma, Mart, Karelson, Mati
I publikationen Int J Mol Sci (2021)

Design and Validation of Novel Chikungunya Virus Protease Inhibitors

av Das, Pratyush Kumar, Puusepp, Laura, Varghese, Finny S., Utt, Age, Ahola, Tero, Kananovich, Dzmitry G., Lopp, Margus, Merits, Andres, Karelson, Mati
I publikationen Antimicrob Agents Chemother (2016)

Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation

av Ivanova, Larisa, Rausalu, Kai, Ošeka, Maksim, Kananovich, Dzmitry G., Žusinaite, Eva, Tammiku-Taul, Jaana, Lopp, Margus, Merits, Andres, Karelson, Mati
I publikationen ACS Omega (2021)

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications

av Mutso, Margit, Nikonov, Andrei, Pihlak, Arno, Žusinaite, Eva, Viru, Liane, Selyutina, Anastasia, Reintamm, Tõnu, Kelve, Merike, Saarma, Mart, Karelson, Mati, Merits, Andres
I publikationen PLoS One (2015)

Novel RET agonist for the treatment of experimental neuropathies

av Viisanen, Hanna, Nuotio, Ulpukka, Kambur, Oleg, Mahato, Arun Kumar, Jokinen, Viljami, Lilius, Tuomas, Li, Wei, Santos, Hélder A, Karelson, Mati, Rauhala, Pekka, Kalso, Eija, Sidorova, Yulia A
I publikationen Mol Pain (2020)

A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

av Sidorova, Yulia A., Bespalov, Maxim M., Wong, Agnes W., Kambur, Oleg, Jokinen, Viljami, Lilius, Tuomas O., Suleymanova, Ilida, Karelson, Gunnar, Rauhala, Pekka V., Karelson, Mati, Osborne, Peregrine B., Keast, Janet R., Kalso, Eija A., Saarma, Mart
I publikationen Front Pharmacol (2017)

Glial Cell Line–Derived Neurotrophic Factor Receptor Rearranged During Transfection Agonist Supports Dopamine Neurons In Vitro and Enhances Dopamine Release In Vivo

av Mahato, Arun Kumar, Kopra, Jaakko, Renko, Juho‐Matti, Visnapuu, Tanel, Korhonen, Ilari, Pulkkinen, Nita, Bespalov, Maxim M., Domanskyi, Andrii, Ronken, Eric, Piepponen, T. Petteri, Voutilainen, Merja H., Tuominen, Raimo K., Karelson, Mati, Sidorova, Yulia A., Saarma, Mart
I publikationen Mov Disord (2019)

Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and Objectives

av Sikorski, Vilbert, Karjalainen, Pasi, Blokhina, Daria, Oksaharju, Kati, Khan, Jahangir, Katayama, Shintaro, Rajala, Helena, Suihko, Satu, Tuohinen, Suvi, Teittinen, Kari, Nummi, Annu, Nykänen, Antti, Eskin, Arda, Stark, Christoffer, Biancari, Fausto, Kiss, Jan, Simpanen, Jarmo, Ropponen, Jussi, Lemström, Karl, Savinainen, Kimmo, Lalowski, Maciej, Kaarne, Markku, Jormalainen, Mikko, Elomaa, Outi, Koivisto, Pertti, Raivio, Peter, Bäckström, Pia, Dahlbacka, Sebastian, Syrjälä, Simo, Vainikka, Tiina, Vähäsilta, Tommi, Tuncbag, Nurcan, Karelson, Mati, Mervaala, Eero, Juvonen, Tatu, Laine, Mika, Laurikka, Jari, Vento, Antti, Kankuri, Esko
I publikationen Int J Mol Sci (2021)