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Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors
[Image: see text] The RNA 6-N-methyladenosine (m6A) demethylase ALKBH5 has been shown to be oncogenic in several cancer types, including leukemia and glioblastoma. We present here the target-tailored development and first evaluation of the antiproliferative effects of new ALKBH5 inhibitors. Two comp...
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| Publicado en: | ACS Omega |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2021
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8158789/ https://ncbi.nlm.nih.gov/pubmed/34056479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01289 |
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