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HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators

[Image: see text] The N6-methyladenosine (m(6)A) modifications in both viral and host cell RNAs play an important role in HIV-1 virus genome transcription and virus replication. We demonstrate here that activators of the METTL3/METTL14/WTAP RNA methyltransferase complex enhance the production of vir...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Selberg, Simona, Žusinaite, Eva, Herodes, Koit, Seli, Neinar, Kankuri, Esko, Merits, Andres, Karelson, Mati
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223420/
https://ncbi.nlm.nih.gov/pubmed/34179640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.1c01626
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