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Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons
The fat mass and obesity-associated protein (FTO), an RNA N(6)-methyladenosine (m(6)A) demethylase, is an important regulator of central nervous system development, neuronal signaling and disease. We present here the target-tailored development and biological characterization of small-molecule inhib...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8123663/ https://ncbi.nlm.nih.gov/pubmed/33926120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094537 |
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