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Rational design and characterization of a Rac GTPase-specific small molecule inhibitor
The signaling pathways mediated by Rho family GTPases have been implicated in many aspects of cell biology. The specificity of the pathways is achieved in part by the selective interaction between Dbl family guanine nucleotide exchange factors (GEFs) and their Rho GTPase substrates. Here, we report...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC419655/ https://ncbi.nlm.nih.gov/pubmed/15128949 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307512101 |
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