Identification of Natural Compounds against Neurodegenerative Diseases Using In Silico Techniques

por Ivanova, Larisa, Karelson, Mati, Dobchev, Dimitar A.
Publicado no Molecules (2018)

Multitarget Approach to Drug Candidates against Alzheimer’s Disease Related to AChE, SERT, BACE1 and GSK3β Protein Targets

por Ivanova, Larisa, Karelson, Mati, Dobchev, Dimitar A.
Publicado no Molecules (2020)

Rational Design of Novel Anticancer Small-Molecule RNA m6A Demethylase ALKBH5 Inhibitors

por Selberg, Simona, Seli, Neinar, Kankuri, Esko, Karelson, Mati
Publicado no ACS Omega (2021)

Small-Molecule Ligands as Potential GDNF Family Receptor Agonists

por Ivanova, Larisa, Tammiku-Taul, Jaana, Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Publicado no ACS Omega (2018)

1,3-Thiazolbenzamide Derivatives as Chikungunya Virus nsP2 Protease Inhibitors

por Ivanova, Larisa, Rausalu, Kai, Žusinaite, Eva, Tammiku-Taul, Jaana, Merits, Andres, Karelson, Mati
Publicado no ACS Omega (2021)

Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands

por Ivanova, Larisa, Tammiku-Taul, Jaana, García-Sosa, Alfonso T., Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Publicado no ACS Omega (2018)

HIV Replication Is Increased by RNA Methylation METTL3/METTL14/WTAP Complex Activators

por Selberg, Simona, Žusinaite, Eva, Herodes, Koit, Seli, Neinar, Kankuri, Esko, Merits, Andres, Karelson, Mati
Publicado no ACS Omega (2021)

Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons

por Selberg, Simona, Yu, Li-Ying, Bondarenko, Olesja, Kankuri, Esko, Seli, Neinar, Kovaleva, Vera, Herodes, Koit, Saarma, Mart, Karelson, Mati
Publicado no Int J Mol Sci (2021)

Design and Validation of Novel Chikungunya Virus Protease Inhibitors

por Das, Pratyush Kumar, Puusepp, Laura, Varghese, Finny S., Utt, Age, Ahola, Tero, Kananovich, Dzmitry G., Lopp, Margus, Merits, Andres, Karelson, Mati
Publicado no Antimicrob Agents Chemother (2016)

Novel Analogues of the Chikungunya Virus Protease Inhibitor: Molecular Design, Synthesis, and Biological Evaluation

por Ivanova, Larisa, Rausalu, Kai, Ošeka, Maksim, Kananovich, Dzmitry G., Žusinaite, Eva, Tammiku-Taul, Jaana, Lopp, Margus, Merits, Andres, Karelson, Mati
Publicado no ACS Omega (2021)

RNA Interference-Guided Targeting of Hepatitis C Virus Replication with Antisense Locked Nucleic Acid-Based Oligonucleotides Containing 8-oxo-dG Modifications

por Mutso, Margit, Nikonov, Andrei, Pihlak, Arno, Žusinaite, Eva, Viru, Liane, Selyutina, Anastasia, Reintamm, Tõnu, Kelve, Merike, Saarma, Mart, Karelson, Mati, Merits, Andres
Publicado no PLoS One (2015)

Novel RET agonist for the treatment of experimental neuropathies

por Viisanen, Hanna, Nuotio, Ulpukka, Kambur, Oleg, Mahato, Arun Kumar, Jokinen, Viljami, Lilius, Tuomas, Li, Wei, Santos, Hélder A, Karelson, Mati, Rauhala, Pekka, Kalso, Eija, Sidorova, Yulia A
Publicado no Mol Pain (2020)

A Novel Small Molecule GDNF Receptor RET Agonist, BT13, Promotes Neurite Growth from Sensory Neurons in Vitro and Attenuates Experimental Neuropathy in the Rat

por Sidorova, Yulia A., Bespalov, Maxim M., Wong, Agnes W., Kambur, Oleg, Jokinen, Viljami, Lilius, Tuomas O., Suleymanova, Ilida, Karelson, Gunnar, Rauhala, Pekka V., Karelson, Mati, Osborne, Peregrine B., Keast, Janet R., Kalso, Eija A., Saarma, Mart
Publicado no Front Pharmacol (2017)

Glial Cell Line–Derived Neurotrophic Factor Receptor Rearranged During Transfection Agonist Supports Dopamine Neurons In Vitro and Enhances Dopamine Release In Vivo

por Mahato, Arun Kumar, Kopra, Jaakko, Renko, Juho‐Matti, Visnapuu, Tanel, Korhonen, Ilari, Pulkkinen, Nita, Bespalov, Maxim M., Domanskyi, Andrii, Ronken, Eric, Piepponen, T. Petteri, Voutilainen, Merja H., Tuominen, Raimo K., Karelson, Mati, Sidorova, Yulia A., Saarma, Mart
Publicado no Mov Disord (2019)

Epitranscriptomics of Ischemic Heart Disease—The IHD-EPITRAN Study Design and Objectives

por Sikorski, Vilbert, Karjalainen, Pasi, Blokhina, Daria, Oksaharju, Kati, Khan, Jahangir, Katayama, Shintaro, Rajala, Helena, Suihko, Satu, Tuohinen, Suvi, Teittinen, Kari, Nummi, Annu, Nykänen, Antti, Eskin, Arda, Stark, Christoffer, Biancari, Fausto, Kiss, Jan, Simpanen, Jarmo, Ropponen, Jussi, Lemström, Karl, Savinainen, Kimmo, Lalowski, Maciej, Kaarne, Markku, Jormalainen, Mikko, Elomaa, Outi, Koivisto, Pertti, Raivio, Peter, Bäckström, Pia, Dahlbacka, Sebastian, Syrjälä, Simo, Vainikka, Tiina, Vähäsilta, Tommi, Tuncbag, Nurcan, Karelson, Mati, Mervaala, Eero, Juvonen, Tatu, Laine, Mika, Laurikka, Jari, Vento, Antti, Kankuri, Esko
Publicado no Int J Mol Sci (2021)