Intrapulmonary Pharmacokinetics of Relebactam, a Novel β-Lactamase Inhibitor, Dosed in Combination with Imipenem-Cilastatin in Healthy Subjects

par Rizk, Matthew L., Rhee, Elizabeth G., Jumes, Patricia A., Gotfried, Mark H., Zhao, Tian, Mangin, Eric, Bi, Sheng, Chavez-Eng, Cynthia M., Zhang, Zufei, Butterton, Joan R.
Publié dans Antimicrob Agents Chemother (2018)

Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Relebactam, a β-Lactamase Inhibitor, in Combination with Imipenem and Cilastatin in Healthy Participants

par Rhee, Elizabeth G., Rizk, Matthew L., Calder, Nicole, Nefliu, Marcela, Warrington, Steven J., Schwartz, Michael S., Mangin, Eric, Boundy, Keith, Bhagunde, Pratik, Colon-Gonzalez, Francheska, Jumes, Patricia, Liu, Yang, Butterton, Joan R.
Publié dans Antimicrob Agents Chemother (2018)

Erratum for Rhee et al., “Pharmacokinetics, Safety, and Tolerability of Single and Multiple Doses of Relebactam, a β-Lactamase Inhibitor, in Combination with Imipenem and Cilastati...

par Rhee, Elizabeth G., Rizk, Matthew L., Calder, Nicole, Nefliu, Marcela, Warrington, Steven J., Schwartz, Michael S., Mangin, Eric, Boundy, Keith, Bhagunde, Pratik, Colon-Gonzalez, Francheska, Jumes, Patricia, Liu, Yang, Butterton, Joan R.
Publié dans Antimicrob Agents Chemother (2018)

Impact of renal impairment and human organic anion transporter inhibition on pharmacokinetics, safety and tolerability of relebactam combined with imipenem and cilastatin

par Bhagunde, Pratik, Colon‐Gonzalez, Francheska, Liu, Yang, Wu, Jin, Xu, Shiyao Sherrie, Garrett, Graigory, Jumes, Patricia, Lasseter, Kenneth, Marbury, Thomas, Rizk, Matthew L., Lala, Mallika, Rhee, Elizabeth G., Butterton, Joan R., Boundy, Keith
Publié dans Br J Clin Pharmacol (2020)

Susceptibilities of Genotype 1a, 1b, and 3 Hepatitis C Virus Variants to the NS5A Inhibitor Elbasvir

par Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Yeh, Wendy W., Ludmerer, Steven W., Jumes, Patricia A., Marshall, William L., Kong, Stephanie, Ingravallo, Paul, Black, Stuart, Pak, Irene, DiNubile, Mark J., Howe, Anita Y. M.
Publié dans Antimicrob Agents Chemother (2015)

No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy

par Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Reitmann, Christina, Jumes, Patricia, Wolford, Dennis, Fraser, Iain, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Webster, Lynn, Yeh, Wendy W.
Publié dans Clin Transl Sci (2018)

No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist Therapy

par Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Barbour, April, Reitmann, Christina, Jumes, Patricia, Gilmartin, Jocelyn, Wolford, Dennis, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Fraser, Iain, Webster, Lynn, Yeh, Wendy W.
Publié dans Clin Transl Sci (2018)

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects

par Thomas, Tiffany, Zhou, Haihong, Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, Liu, Yang, Jumes, Patricia, Wagner, John A., Hubbard, Brian, Previs, Stephen F., Roddy, Thomas, Johnson-Levonas, Amy O., Gutstein, David E., Marcovina, Santica M., Rader, Daniel J., Ginsberg, Henry N., Millar, John S., Reyes-Soffer, Gissette
Publié dans Arterioscler Thromb Vasc Biol (2017)

Measurement of apo(a) kinetics in human subjects using a microfluidic device with tandem mass spectrometry

par Zhou, Haihong, Castro-Perez, Jose, Lassman, Michael E., Thomas, Tiffany, Li, Wenyu, McLaughlin, Theresa, Dan, Xie, Jumes, Patricia, Wagner, John A., Gutstein, David E., Hubbard, Brian K., Rader, Daniel J., Millar, John S., Ginsberg, Henry N., Reyes-Soffer, Gissette, Cleary, Michele, Previs, Stephen F., Roddy, Thomas P.
Publié dans Rapid Commun Mass Spectrom (2013)

Effects of CETP inhibition with anacetrapib on metabolism of VLDL-TG and plasma apolipoproteins C-II, C-III, and E

par Millar, John S., Lassman, Michael E., Thomas, Tiffany, Ramakrishnan, Rajasekhar, Jumes, Patricia, Dunbar, Richard L., deGoma, Emil M., Baer, Amanda L., Karmally, Wahida, Donovan, Daniel S., Rafeek, Hashmi, Wagner, John A., Holleran, Stephen, Obunike, Joseph, Liu, Yang, Aoujil, Soumia, Standiford, Taylor, Gutstein, David E., Ginsberg, Henry N., Rader, Daniel J., Reyes-Soffer, Gissette
Publié dans J Lipid Res (2017)

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

par Millar, John S., Reyes-Soffer, Gissette, Jumes, Patricia, Dunbar, Richard L., deGoma, Emil M., Baer, Amanda L., Karmally, Wahida, Donovan, Daniel S., Rafeek, Hashmi, Pollan, Laura, Tohyama, Junichiro, Johnson-Levonas, Amy O., Wagner, John A., Holleran, Stephen, Obunike, Joseph, Liu, Yang, Ramakrishnan, Rajasekhar, Lassman, Michael E., Gutstein, David E., Ginsberg, Henry N., Rader, Daniel J.
Publié dans J Clin Invest (2015)

Anacetrapib lowers LDL by increasing ApoB clearance in mildly hypercholesterolemic subjects

par Millar, John S., Reyes-Soffer, Gissette, Jumes, Patricia, Dunbar, Richard L., deGoma, Emil M., Baer, Amanda L., Karmally, Wahida, Donovan, Daniel S., Rafeek, Hashmi, Pollan, Laura, Tohyama, Junichiro, Johnson-Levonas, Amy O., Wagner, John A., Holleran, Stephen, Obunike, Joseph, Liu, Yang, Ramakrishnan, Rajasekhar, Lassman, Michael E., Gutstein, David E., Ginsberg, Henry N., Rader, Daniel J.
Publié dans J Clin Invest (2016)

CETP inhibition with Anacetrapib Decreases Fractional Clearance Rates of HDL Apolipoprotein A-I and Plasma CETP

par Reyes-Soffer, Gissette, Millar, John S., Ngai, Colleen, Jumes, Patricia, Coromilas, Ellie, Asztalos, Bela, Johnson-Levonas, Amy O., Wagner, John A., Donovan, Daniel S., Karmally, Wahida, Ramakrishnan, Rajasekhar, Holleran, Stephen, Thomas, Tiffany, Dunbar, Richard L., deGoma, Emil M., Rafeek, Hashmi, Baer, Amanda L., Liu, Yang, Lassman, Michael E., Gutstein, David E., Rader, Daniel J., Ginsberg, Henry N.
Publié dans Arterioscler Thromb Vasc Biol (2016)

Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Health...

par Feng, Hwa-Ping, Caro, Luzelena, Fandozzi, Christine, Chu, Xiaoyan, Guo, Zifang, Talaty, Jennifer, Panebianco, Deborah, Dunnington, Katherine, Du, Lihong, Hanley, William D., Fraser, Iain P., Mitselos, Anna, Denef, Jean-Francois, De Lepeleire, Inge, de Hoon, Jan N., Vandermeulen, Corinne, Marshall, William L., Jumes, Patricia, Huang, Xiaobi, Martinho, Monika, Valesky, Robert, Butterton, Joan R., Iwamoto, Marian, Yeh, Wendy W.
Publié dans Antimicrob Agents Chemother (2019)