No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Buprenorphine/Naloxone in Healthy Participants and Participants Receiving Stable Opioid Agonist Therapy

The aims of these phase I trials were to evaluate the pharmacokinetic interaction between elbasvir (EBR) or grazoprevir (GZR) and buprenorphine/naloxone (BUP/NAL). Trial 1 was a single‐dose trial in healthy participants. Trial 2 was a multiple‐dose trial in participants on BUP/NAL maintenance therap...

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Foilsithe in:Clin Transl Sci
Main Authors: Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Barbour, April, Reitmann, Christina, Jumes, Patricia, Gilmartin, Jocelyn, Wolford, Dennis, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Fraser, Iain, Webster, Lynn, Yeh, Wendy W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2018
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226112/
https://ncbi.nlm.nih.gov/pubmed/30040871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12565
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