No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy

We conducted two phase I trials to evaluate the pharmacokinetic interactions between elbasvir (EBR), grazoprevir (GZR), and methadone (MK‐8742‐P010 and MK‐5172‐P030) in non‐hepatitis C virus (HCV)‐infected participants on methadone maintenance therapy. Coadministration of EBR or GZR with methadone h...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Transl Sci
Päätekijät: Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Reitmann, Christina, Jumes, Patricia, Wolford, Dennis, Fraser, Iain, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Webster, Lynn, Yeh, Wendy W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2018
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226122/
https://ncbi.nlm.nih.gov/pubmed/30040872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12564
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