No Pharmacokinetic Interactions Between Elbasvir or Grazoprevir and Methadone in Participants Receiving Maintenance Opioid Agonist Therapy

We conducted two phase I trials to evaluate the pharmacokinetic interactions between elbasvir (EBR), grazoprevir (GZR), and methadone (MK‐8742‐P010 and MK‐5172‐P030) in non‐hepatitis C virus (HCV)‐infected participants on methadone maintenance therapy. Coadministration of EBR or GZR with methadone h...

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Bibliografiska uppgifter
I publikationen:Clin Transl Sci
Huvudupphovsmän: Feng, Hwa‐Ping, Guo, Zifang, Caro, Luzelena, Marshall, William L., Liu, Fang, Panebianco, Deborah, Vaddady, Pavan, Reitmann, Christina, Jumes, Patricia, Wolford, Dennis, Fraser, Iain, Valesky, Robert, Martinho, Monika, Butterton, Joan R., Iwamoto, Marian, Webster, Lynn, Yeh, Wendy W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2018
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226122/
https://ncbi.nlm.nih.gov/pubmed/30040872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12564
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