Susceptibilities of Genotype 1a, 1b, and 3 Hepatitis C Virus Variants to the NS5A Inhibitor Elbasvir

Elbasvir is an investigational NS5A inhibitor with in vitro activity against multiple HCV genotypes. Antiviral activity of elbasvir was measured in replicons derived from wild-type or resistant variants of genotypes 1a, 1b, and 3. The barrier to resistance was assessed by the number of resistant col...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Yeh, Wendy W., Ludmerer, Steven W., Jumes, Patricia A., Marshall, William L., Kong, Stephanie, Ingravallo, Paul, Black, Stuart, Pak, Irene, DiNubile, Mark J., Howe, Anita Y. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604396/
https://ncbi.nlm.nih.gov/pubmed/26303801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01390-15
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