Susceptibilities of Genotype 1a, 1b, and 3 Hepatitis C Virus Variants to the NS5A Inhibitor Elbasvir

Elbasvir is an investigational NS5A inhibitor with in vitro activity against multiple HCV genotypes. Antiviral activity of elbasvir was measured in replicons derived from wild-type or resistant variants of genotypes 1a, 1b, and 3. The barrier to resistance was assessed by the number of resistant col...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Yeh, Wendy W., Ludmerer, Steven W., Jumes, Patricia A., Marshall, William L., Kong, Stephanie, Ingravallo, Paul, Black, Stuart, Pak, Irene, DiNubile, Mark J., Howe, Anita Y. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604396/
https://ncbi.nlm.nih.gov/pubmed/26303801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01390-15
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