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Susceptibilities of Genotype 1a, 1b, and 3 Hepatitis C Virus Variants to the NS5A Inhibitor Elbasvir

Elbasvir is an investigational NS5A inhibitor with in vitro activity against multiple HCV genotypes. Antiviral activity of elbasvir was measured in replicons derived from wild-type or resistant variants of genotypes 1a, 1b, and 3. The barrier to resistance was assessed by the number of resistant col...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Liu, Rong, Curry, Stephanie, McMonagle, Patricia, Yeh, Wendy W., Ludmerer, Steven W., Jumes, Patricia A., Marshall, William L., Kong, Stephanie, Ingravallo, Paul, Black, Stuart, Pak, Irene, DiNubile, Mark J., Howe, Anita Y. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604396/
https://ncbi.nlm.nih.gov/pubmed/26303801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01390-15
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