N-Heterocyclic Carbene Capture by Cytochrome P450 3A4

Por Jennings, Gareth K., Ritchie, Caroline M., Shock, Lisa S., Lyons, Charles E., Hackett, John C.
Publicado no Mol Pharmacol (2016)

Noncovalent interactions dominate dynamic heme distortion in cytochrome P450 4B1

Por Jennings, Gareth K., Hsu, Mei-Hui, Shock, Lisa S., Johnson, Eric F., Hackett, John C
Publicado no J Biol Chem (2018)

Evidence for an Elevated Aspartate pK(a) in the Active Site of Human Aromatase

Por Di Nardo, Giovanna, Breitner, Maximilian, Bandino, Andrea, Ghosh, Debashis, Jennings, Gareth K., Hackett, John C., Gilardi, Gianfranco
Publicado no J Biol Chem (2015)

Biophysical Characterization of Aptenodytes forsteri Cytochrome P450 Aromatase

Por Zarate-Perez, Francisco, Velázquez-Fernández, Jesús B., Jennings, Gareth K., Shock, Lisa S., Lyons, Charles E., Hackett, John C
Publicado no J Inorg Biochem (2018)

Spin equilibrium and O(2)-binding kinetics of Mycobacterium tuberculosis CYP51 with mutations in the histidine–threonine dyad

Por Jennings, Gareth K., Modi, Anuja, Elenewski, Justin E., Ritchie, Caroline M., Nguyen, Thuy, Ellis, Keith C., Hackett, John C
Publicado em 2014

Rapid Chagas disease drug target discovery using directed evolution in drug-sensitive yeast

Por Ottilie, Sabine, Goldgof, Gregory M., Calvet, Claudia Magalhaes, Jennings, Gareth K., LaMonte, Greg, Schenken, Jake, Vigil, Edgar, Kumar, Prianka, McCall, Laura-Isobel, Lopes, Eduardo Soares Constantino, Gunawan, Felicia, Yang, Jennifer, Suzuki, Yo, Siqueira-Neto, Jair L., McKerrow, James H., Amaro, Rommie E., Podust, Larissa M., Durrant, Jacob D., Winzeler, Elizabeth A.
Publicado no ACS Chem Biol (2016)